Quiz
Antigen Presentation
Questions in this quiz (22)
1B Cells recognise native antigens, T cells recognise processed antigens
- ATrue
- BFalse
2Which of the following are NOT professional antigen presenting cells?
- ANeutrophils
- BMacrophages
- CDendritic cells
3CD8 T-cells recognise which MHC complex?
- AMHCI
- BMHCII
4CD4 is for the detection of virally infected cells
- ATrue
- BFalse
5CD4 cells recognise MHCII, which uses which Antigen processing system?
- AEndosomal
- BEndogenous
- CEndomal
6Cells with MHCI present using the endogenous AP system
- ATrue
- BFalse
7T- cells cannot recognise soluble, native antigens
- ATrue
- BFalse
8Put the following steps in the correct order- A (Antigen-MHC Complex Formation), B (Uptake), C (Presentation) and D (Degredation
- AB-D-A-C
- BA-B-D-C
- CA-C-B-D
9Which of the following definitions is incorrect?
- AUptake- picking up of the antigen from surrounding fluid
- BDegredation- total digestion of the antigen
- CPresentation- movement of the complex to the cell surface
10Endosomal Pathway- What is it for?
- AProcessing of extracellular antigens picked up by antigen presenting cells
- BProcessing of cytosolic viral antigens
11Endosomal Pathway- Uses the MHCI complex
- ATrue
- BFalse
12Endosomal Pathway- The extracellular antigen is picked up by phagocytosis
- ATrue
- BFalse
13Endosomal Pathway- How is picking up of the antigen mediated?
- AReceptor mediated
- BCompliment mediated
- CHormone mediated
14Endosomal Pathway- The antigen containing endosome only binds to the MCHII containing endosome after partial digestion
- ATrue
- BFalse
15Endosomal Pathway- How is the active site of MHCII covered in the cell?
- ACovered by an invariant 'cap'
- BThe two parts are connect by a subunit that must be removed
- CReceptor surface is bound to the endosome envelope
16Endosomal Pathway- The cover of the MHC complex is called a CLIP
- ATrue
- BFalse
17Endosomal Pathway- How is the processed antigen added to the MHCII complex?
- AAcessory proteins swap the CLIP for the peptide when the two vesicles fuse
- BAcessory proteins remove the MHCII from the envelope when the two vesicles fuse
- CAcessory proteins remove the subunit connecting the two halves when the two vesicles fuse
18Endogenous Pathway- Main use is for what?
- AViral antigen processing
- BProfessional pesentation of antigens
19Endogenous Pathway uses MHCII
- ATrue
- BFalse
20Endogenous Pathway- How are cytosolic antigens processed?
- ABy the TCR
- BBy MHCI
- CBy cytosolic proteases
21Endogenous Pathway- Digested peptides are moved into the Golgi by what?
- ATransporter Associated with Antigen Processing (TAP 1&2)
- BTransporter Associated with Antigen Digestion (TAD 1&2)
- CTransporter Associated with Antigen Presentation (TAP 1&2)
22In the Golgi the processed peptide is bound to MHCI and they complex is loaded into a vesicle for transport to the cell membrane
- ATrue
- BFalse
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- Description
- Year 2 Quiz on Antigen Presentation, created by gina_evans0312 on 13/03/2014.
- Author
- gina_evans0312
- Language
- English
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