Flashcards
Carbohydrates, Metabolism & spectrometry
Cards in this deck (20)
- 1What are alpha and beta sugars?If OH on same face as anomeric carbon (cis)= beta/ If on opposite face (trans)=alpha
- 2What location defines a D and L sugar?If OH on left=L on right=D
- 3What is an epimer?a diastereoisomer that differs in configuration at only one of the stereogenic centres
- 4What is an anomer?A type of an epimer that differs in configuration at the anomeric position
- 5How does metabolism help excretion of drugs?By increasing polarity and water solubility of the drugs
- 6glucose+glucose=maltose
- 7glucose+fructose=sucrose
- 8Describe the process of mass spectrometrythe sample is vaporised and high energy electrons are fired at it causing part of the sample to be ejected=charged ion. A detector sorts charged ions into the relative mass-to-charge ratios and determines the relative amounts of each
- 9what is a base peak?Most intense signal which arise from bond cleavages that occur readily
- 10Name two unfavourable fragmentsCH3+ and H+
- 11What would be seen in a mass spec if there was an aromatic next to a Ch2?peak at 91 due to [C7H7]+ and a peak at 65 due to loss of ethane
- 12What is the molecular peak for an acylium cation on a mass spec? [COCH3]+. why is this stable?43 because cleaving next to a carbonyl is stable because +ve charge can be delocalised onto both oxygen and carbon so more spread out
- 13What is the peak found for a phenyl cation? [C6H5]+77
- 14name some monoisotopic elements?F, I, P
- 15What elements have a low abundance of other isotypes?H + N
- 16What elements have variations?Cl, Br, S, Si, C
- 17What does a 75:25% ratio suggest?Cl
- 18What does a 50:50% ratio suggest?Br
- 19What is MALDI?softer technique, produces molecular ion with one positive charge-molecular weight of molecular more easily determined
- 20What is ESI?Softer technique, adds protons instead of electrons, produces multiple charges meaning multiple m/z values for same molecule
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- undergrad Chemistry Flashcards on Carbohydrates, Metabolism & spectrometry, created by tanitia.dooley on 15/05/2013.
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