323913
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
|
Creado por gina_evans0312
hace más de 10 años
|
|
Pregunta 1
Pregunta
What is so special about cGMPPK?
Respuesta
-
It's anti-parallel
-
The subunits of the dimer can swap roles of damage occurs
-
It's only found in cardiac cells
Pregunta 2
Pregunta
How many cGMP bind per monomer?
Respuesta
-
2
-
4
-
6
-
1
-
3
Pregunta 3
Pregunta
Which order do the subunits go in (from N to C terminus)
A= Dimerisation Domain
B- Catalytic Domain
C= Autoinhibitory Hinge Region
D= cGMP binding sites 1 & 2
Respuesta
-
A-C-D-B
-
A-B-D-C
-
C-A-D-B
-
C-D-A-B
Pregunta 4
Pregunta
What is the purpose of the autoinhibitory hinge region?
Respuesta
-
Acts as a pseudosubstrate
-
Causes inhibition after a certain amount of activity
Pregunta 5
Pregunta
What motif does cGMP Stimulated Protein Kinase Phosphorylate?
Respuesta
-
Arg-Ser-X-Arg
-
Arg-Thr-X-Arg
-
Arg-Arg-X-Ser
-
Arg-Arg-X-Thr
Pregunta 6
Pregunta
What is the role of this protein?
Respuesta
-
The activation of cGMP dependent ion channels
-
Activates cGMP dependent phosphodiesterases
-
The activation of cGMP dependent proteins
-
Inhibits cGMP dependent phosphodiesterases
Pregunta 7
Pregunta
What is required for NO to be synthesized?
Respuesta
-
NO synthase
-
FMD/FAD
-
O2
-
NADP
-
NADPH
-
FMD
-
Tetrahydrobiopterin
Pregunta 8
Pregunta
Which of the following stimulate NO production?
A- AcH
B- Bradylunin
C- Nicotine
D- Thrombin
E- Cl-
F- Ca2+
Respuesta
-
A, B, D, F
-
A, D, E, F
-
B, C, D, F
Pregunta 9
Pregunta
Which system is NO part of?
Respuesta
-
Paracrine
-
Juxtracrine
-
Autocrine
-
Endocrine
Pregunta 10
Pregunta
NO is synthase a monomer- True or False?
Respuesta
-
True
-
False
Pregunta 11
Pregunta
How many types of NO synthase are there?
Respuesta
-
Constitutive
-
Inducible
-
Constitutive & Inudcible
Pregunta 12
Pregunta
Why is NO produced by iNOS (Immune NO Synthase)
Respuesta
-
It kills of pathogens
-
It's used to signal immune cells
-
It's used to bind and immobalise pathogens
Pregunta 13
Pregunta
NO Synthase produces a few mmol of NO over a minute- True or False?
Respuesta
-
True
-
False- its pmol over a minute
-
False, it's micromol in a few seconds
-
False, its pmol over a few seconds
Pregunta 14
Pregunta
NO Synthase contains the following, but in which order?
A-NADPH binding site
B-Calmodulin Binding Site
C-FMN centre
D- FAD centre
E-Haeme group
F- Arg, O2 and Tetrahydropterin (Active site)
Respuesta
-
E-F-B-C-D-A
-
A-D-B-C-F-E
-
E-F-A-C-D-B
Pregunta 15
Pregunta
Why are vascular endothelial cells equipped to cause vasodilation?
Respuesta
-
It allows them to reduce blood pressure according to need
-
It allows them to increase blood flow to wounded areas
-
It prevents damage to veins under high pressure
Pregunta 16
Pregunta
Which neurotransmitter effects which cells?
A- Ach
B-Vasopressin
Respuesta
-
Vascular Endothelial-A Skeletal Muscle-B
-
Vascular Endothelial- A&B Skeletal Muscle-A
-
Vascular Endothelial- A Skeletal Muscle-A&B
Pregunta 17
Pregunta
What is the role of nitroglycerin?
Respuesta
-
An explosive
-
It liberates NO from tissues
-
Causes an increase in NO synthesis
Pregunta 18
Pregunta
What is the role of viagra?
Respuesta
-
Inhibits phosphodiesterases
-
Prevents cGMP breakdown
-
Prolongs NO production
¿Quieres crear tus propios Tests gratis con GoConqr? Más información.