Cell & Muscle Signalling

gina_evans0312
Quiz by , created over 5 years ago

Year 2 Quiz on Cell & Muscle Signalling, created by gina_evans0312 on 10/20/2013.

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gina_evans0312
Created by gina_evans0312 over 5 years ago
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Question 1

Question
What effect does extracellular homeostasis have on intracellular homeostasis?
Answer
  • It overrides it
  • It is overridden by it
  • It has no effect

Question 2

Question
What type of messenger is released by extodermal shedding?
Answer
  • Membrane bound
  • Direct diffusion
  • Vesicle bound

Question 3

Question
How are cytoplasmic formed chemical messengers released?
Answer
  • Lipophillic diffusion through the membrane
  • Dedicated passenger proteins
  • Hydrophillic diffusion through the membrane

Question 4

Question
What Mr can be passed through direct diffusion?
Answer
  • Low
  • Moderate
  • High

Question 5

Question
Which part of the myosin in the musce fibre contains the ATPase?
Answer
  • Hinge region
  • Light chain
  • Heavy chain

Question 6

Question
What make up the Troponin complex in muscle?
Answer
  • Troponin C
  • Troponin I
  • Troponin T
  • Actin
  • Myosin

Question 7

Question
Why is the sarcomere pronounced as a 'cell unit'?
Answer
  • Muscles are polynucleatre
  • Sarcomeres are the largest subunit
  • They are the only subunits containing both actin/myosin

Question 8

Question
What muscular receptors are effected by Ach?
Answer
  • Nicotinic Ach receptors
  • Adeninic Ach receptors
  • Adrenergic Ach receptors

Question 9

Question
How long is the half life of Ach
Answer
  • 1-2 secs
  • 10-20 secs
  • 4-5 secs

Question 10

Question
How many subunits make up Nicotinic Ach Receptors?
Answer
  • 5- 2 alpha, a beta a delta and a gamma
  • 5- an alpha, 2 beta, a delta and a gamma
  • 5- an alpha, a beta, 2 delta and a gamma

Question 11

Question
All subunits in Nicotinic Ach Receptors have a transmembrane domain of 4 helices- which one is ampipathic?
Answer
  • M1
  • M2
  • M3
  • M4

Question 12

Question
When Ach binds, the subunits twist to replace an amino acid with an inorgaic ion. Name them.
Answer
  • Leucine is replaced with Phosphate
  • Tyrosine is replace with Sodium
  • Serine is replace with Chlorine

Question 13

Question
When the impulse enters the muscle cell, what channels are opened in the T-tubule?
Answer
  • DHP
  • AHP
  • CHP

Question 14

Question
Once the DHP receptor has been opened, which receptor does it open in the Sarcoplasmic Reticulum?
Answer
  • Ryonadine
  • Acetylcholamine
  • Phosphodine

Question 15

Question
What keeps the Ca2+ concentration in the sarcoplasmic reticulum so high?
Answer
  • ATP driven Ca2+ pumps
  • Ca2+/Cl- co-transporters
  • Ca2+/Na+ exchange

Question 16

Question
Of the transmembrane helices in DHP, which do which jobs?
Answer
  • S4 - voltage sensing S5-6 form pores
  • S5-6 - voltage sensing S4-form pores
  • S2 - voltage sensing S3-4 form pores

Question 17

Question
What allows the DHP receptor to communicate with the Ryonadine receptor?
Answer
  • Loops II-III
  • Loops III-IV
  • Loops I-II

Question 18

Question
In the ryonadine receptor, the 6 hydrophobic helices are found in make up how many identical subunits?
Answer
  • 4
  • 5
  • 6
  • 7

Question 19

Question
The pore is formed in ryonadine receptors by what?
Answer
  • The loops between S9 & S10
  • The loops between S10 & S11
  • The loops between S8 & S9

Question 20

Question
What protein holds the Ca2+ inside the sarcoplasmic reticulum for extra security?
Answer
  • Calsequestrin
  • Calcitachin
  • Calcibindin

Question 21

Question
Which subunit of the dihydropyridine receptor contains 4 homologous transmembrane domains?
Answer
  • Alpha 1
  • Beta
  • Alpha 2
  • Gamma

Question 22

Question
How many helices make up each one of the four homologous transmembrane domains in the alpha one subunit of Dihydropyridine receptor?
Answer
  • 6
  • 4
  • 8