451493
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312
hace más de 10 años
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Pregunta 1
Pregunta
What is the main problem of protein translocation?
Respuesta
-
Hydrophillic proteins must transverse two hydrophobic membranes and a hydrophillic space
-
Proteins must be unfolded and refolded again
-
Proteins must pass through an extremely crowded cytoplasm
Pregunta 2
Pregunta
Proteins to be secreted directly after translation have a peptidase sequence at the C-terminus
Respuesta
- True
- False
Pregunta 3
Pregunta
Which of the following parts of the peptidase sequence are closest to the N-terminus?
Respuesta
-
The basic residues
-
The hydrophobic region
-
Peptidase cleavage recognition site
Pregunta 4
Pregunta
There are 1-2 basic residues in the signal sequence, but the hydrophobic sequence is variable in length
Respuesta
- True
- False
Pregunta 5
Pregunta
When a protein is transcribed with the Peptidase signal site, what protein binds to its hydrophobic region?
Respuesta
-
Signal Recognition Protein
-
Ftsy- a GTPase
-
SecYEG- a bacterial pore
Pregunta 6
Pregunta
Ftsy transfers the protein into the pore
Respuesta
- True
- False
Pregunta 7
Pregunta
Which of the following provide the driving force for protein translocation across the membrane
Respuesta
-
Protonmotive force
-
FtsY's GTPase
-
Protein translation
Pregunta 8
Pregunta
What binds to the nascent polypeptide if Post-Translational Translocation takes place?
Respuesta
-
SecB
-
SecA
-
SecC
Pregunta 9
Pregunta
Post-Translational Translocation sequences have a string of hydrophobic amino acids, same as in Translational Translocation
Respuesta
- True
- False
Pregunta 10
Pregunta
What is the role of Sec_ ?
Respuesta
-
To keep the protein in solution till it binds to SecA at the pore
-
To fold the protein on its way to the periplasmic more
-
To stop the protein folding on its way to SecC
Pregunta 11
Pregunta
What forces are required to get a Post-Translational Translocation through the pore?
Respuesta
-
GTPase of FtsY
-
ATP hydrolysis by SecB
-
Protonmotive Force
Pregunta 12
Pregunta
Once inside the required membrane, what protein removes the peptide sequence?
Respuesta
-
Signal peptidase
-
Signal lyase
-
Signal Isomerase
Pregunta 13
Pregunta
The protein only folds after the signal sequence is cleaved
Respuesta
- True
- False
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