Virology (week 3 and 4)

Descripción

DVM2 Virology Test sobre Virology (week 3 and 4), creado por Kathryn Borg el 26/04/2016.
Kathryn Borg
Test por Kathryn Borg, actualizado hace más de 1 año
Kathryn Borg
Creado por Kathryn Borg hace alrededor de 8 años
18
2

Resumen del Recurso

Pregunta 1

Pregunta
Correctly describe the family of Poxviridae
Respuesta
  • Large complex structured viruses with a single molecule of ds DNA
  • Large complex structured viruses with a two molecules of ds RNA
  • Large complex structured viruses with a single molecule of ss DNA
  • Small complex structured viruses with a single molecule of ss DNA

Pregunta 2

Pregunta
What are the two sub-families within Poxviridae?
Respuesta
  • Chordopoxvirinae
  • Entomopoxvirinae
  • Alphaherpesvirinae
  • Papillomavirus
  • Orbivirus

Pregunta 3

Pregunta
What is this lesion?
Respuesta
  • Pock
  • Pustule
  • Ulceration
  • Macule

Pregunta 4

Pregunta
What is the correct pathogenesis of a pock lesion?
Respuesta
  • Raised, reddened macule-->papule--> fluid filled vesicle-->Ruptures to form a crater (pock)-->Scarring
  • papule--> Raised, reddened macule--> fluid filled vesicle-->Ruptures to form a crater (pock)-->Scarring
  • fluid filled vesicle-->papule--> Raised, reddened macule-->Ruptures to form a crater (pock)-->Scarring

Pregunta 5

Pregunta
What is true of pox viruses?
Respuesta
  • Duration of immunity < life span of recovered animal
  • Reinfection possible
  • Surviving animals are NOT long term carriers
  • Infectious virus survives for years in infected material (scabs)
  • Pox viruses are very resistant in the environment
  • Surviving animals ARE long term carriers
  • Pox viruses are labile in the environment
  • Immunity is for life

Pregunta 6

Pregunta
Poxvirus transmission between animals may occur by?
Respuesta
  • Mechanical transmission
  • Respiratory route by droplets
  • Via abraded skin

Pregunta 7

Pregunta
Label this diagram correctly. Matching the correct genus with the virus groups (a-f)
Respuesta
  • Orthopoxvirus
  • Parapoxvirus
  • Capripoxvirus
  • Avipoxvirus
  • Suipoxvirus
  • Leporipoxvirus

Pregunta 8

Pregunta
What is true of cowpox?
Respuesta
  • Rodent reservoir
  • Endemic in Europe and Russia and exotic to Australia
  • Results in pock lesions on teats
  • Can affect humans causing maculopapular lesions on hands and face
  • Can affect domestic and large cats
  • Endemic to Australia
  • Mosquito reservoir

Pregunta 9

Pregunta
Sheeppox, Lumpy skin disease and Goat pox are closely related viruses that are indistinguishable by serological assays
Respuesta
  • True
  • False

Pregunta 10

Pregunta
How might an animal become infected by a Capripoxvirus (sheeppox, lumpy skin disease and goat pox)?
Respuesta
  • Skin abrasions
  • Inhalation of aerosols
  • Vector transmission
  • Gastrointestinal tract infection

Pregunta 11

Pregunta
Where are the Capripoxviruses (sheeppox, lumpy skin disease and goat pox) endemic to?
Respuesta
  • Endemic in SE Europe, Middle East, Africa and Asia
  • Endemic in North America, Northern Europe and Australia
  • Endemic in North America and Australia
  • Endemic in North America, the UK, Africa and Asia

Pregunta 12

Pregunta
What is the pathogenesis of the Capripoxviruses (sheeppox, lumpy skin disease and goat pox)?
Respuesta
  • Replicates locally in skin
  • Replicates in lungs following inhalation
  • Can spread to regional lymph nodes
  • Replicates in the gut when swallowed
  • Replicates in lymphocytes

Pregunta 13

Pregunta
What is the incubation period of the Capripoxviruses (sheeppox, lumpy skin disease and goat pox)?
Respuesta
  • ~ 1 week
  • ~ 3 weeks
  • ~ 2 weeks
  • ~ 1 day

Pregunta 14

Pregunta
How might fowl pox be transmitted between animals?
Respuesta
  • Mechanical transmission via mosquitos
  • Aerosol transmission
  • GIT transmission

Pregunta 15

Pregunta
Fowl pox is found within what genus of poxviridae?
Respuesta
  • Avipoxvirus
  • Capripoxvirus
  • Orthopoxvirus
  • Parapoxvirus

Pregunta 16

Pregunta
What is the Parapoxviruses Orf also called?
Respuesta
  • Scabby Mouth
  • Contagious pustular dermatitis
  • Contagious ecthyma

Pregunta 17

Pregunta
What is this disease most likely to be if it is from the poxviridae family?
Respuesta
  • Orf
  • Bovine Papilloma virus
  • Foot and mouth disease

Pregunta 18

Pregunta
What is true of the pathogenesis and epidemiology of Orf?
Respuesta
  • Papular lesions progress to vesicles, pustules and then scabs
  • Lesions heal within 4 weeks (if no secondary bacterial infection)
  • Replicates in epidermal keratinocytes
  • Controlled by virulent vaccination
  • Lesions usually on lips and muzzle (feet, genitalia and teats)
  • Maintained in flocks by chronic carriers
  • Transmission via abrasions
  • Primarily a disease of young sheep
  • There are NO carrier animals
  • There is no vaccination available

Pregunta 19

Pregunta
What is Myxomatosis?
Respuesta
  • A poxvirus disease of rabbits
  • A papillomavirus disease of dogs
  • A poxvirus disease of dogs
  • A poxvirus disease of cats

Pregunta 20

Pregunta
Correctly describe the family of Asfarviridae?
Respuesta
  • They are complex enveloped double stranded DNA virus
  • They are complex enveloped single stranded DNA virus
  • They are complex non-enveloped double stranded DNA virus
  • They are complex enveloped double stranded RNA virus
  • They are complex non-double stranded RNA virus

Pregunta 21

Pregunta
Asfarviridae is Stable in the environment over a wide range of temperatures (4‐20oC) and a wide range of pH. It may persist for months in meat of infected pigs.
Respuesta
  • True
  • False

Pregunta 22

Pregunta
Which of the below viruses belong to the family Asfarviridae?
Respuesta
  • African Swine Fever Virus
  • African Horse Sickness
  • Foot and Mouth Disease (FMD)
  • Contagious pustular dermatitis

Pregunta 23

Pregunta
What animals can Asfarviridae infect?
Respuesta
  • Soft ticks (Ornithodorus moubata and O erraticus)
  • Suidae (eg. pigs, warthogs)
  • Felidae (Domestic cats, lions, tigers)
  • Bovidae (cattle, ox)
  • Canidae (dogs, wolves)
  • Blow flies (Lucillia cuprina, Calliphora stygia)

Pregunta 24

Pregunta
Is a vaccine available for African Swine Fever Virus?
Respuesta
  • Yes
  • No

Pregunta 25

Pregunta
Where does the virus grow within the body?
Respuesta
  • In the reticuloendothelial system
  • In the respiratory sytem
  • In the nervous system
  • In the gastrointestinal system

Pregunta 26

Pregunta
Are there carriers of African swine fever virus?
Respuesta
  • Yes
  • No

Pregunta 27

Pregunta
Why might an animal with African Swine Fever Virus die?
Respuesta
  • Extensive haemorrhages in all organs due to platelet damage and complement activation
  • Damage to the CNS causing the lungs to collapse
  • Oedamatous fluid in the lungs

Pregunta 28

Pregunta
Describe the Herpesviruses?
Respuesta
  • Enveloped double stranded DNA viruses
  • Non-Enveloped double stranded DNA viruses
  • Enveloped single stranded DNA viruses
  • Non-enveloped single stranded DNA viruses

Pregunta 29

Pregunta
Why are the herpesviruses labile in environment and easily inactivated by heat, detergents, pH and drying?
Respuesta
  • They are enveloped viruses
  • They are non-enveloped viruses
  • They are capsulated viruses

Pregunta 30

Pregunta
How are Herpesviruses transmitted?
Respuesta
  • Close or mucosal contact for transmission (droplet)
  • GIT transmission
  • Vector transmission

Pregunta 31

Pregunta
What is the key feature of Herpesviruses?
Respuesta
  • They cause a lifelong latent infection
  • They cause 100% mortality in the infected
  • Infection results in lifelong immunity

Pregunta 32

Pregunta
What are the sub families of Herpesviridae?
Respuesta
  • Alphaherpesvirinae
  • Gammaherpesvirinae
  • Betaherpesvirinae
  • Deltaherpesvirinae
  • Alloherpesvirinae

Pregunta 33

Pregunta
Match the correct virus sub families to their features
Respuesta
  • Gammaherpesvirinae
  • Betaherpesvirinae
  • Alphaherpesvirinae
  • Deltaherpesvirinae

Pregunta 34

Pregunta
Bovine herpesvirus 1 (Infectious bovine rhinotracheitis virus) can manifest as which of the below clinical diseases?
Respuesta
  • Rhinotracheitis
  • Generalised disease of newborn calves
  • Enteritis
  • Abortion
  • Conjunctivitis
  • Balanoposthitis
  • Vulvovaginitis

Pregunta 35

Pregunta
How is Bovine Herpesvirus 1 transmitted?
Respuesta
  • Respiratory route and cell associated viraemia to distant sites
  • GIT route
  • Fomites
  • Vector transmission

Pregunta 36

Pregunta
Bovine herpesvirus 2 -- Bovine mammillitis virus (Pseudo‐lumpy skin disease virus) can cause which of the below forms of clinical disease
Respuesta
  • Mammillitis. Lesions localised to the teats.
  • Generalised skin lesions. Nodules & necrosis of the superficial epidermis
  • Abortion
  • Rhinotracheitis

Pregunta 37

Pregunta
Bovine herpes virus 5 causes?
Respuesta
  • Fatal meningoencephalitis in calves thought to be due to direct neural spread from nasopharynx via trigeminal nerve
  • Respiratory disease, abortion and neurological disease in foals
  • Acute respiratory disease characterised by nasal discharge and lymphadenopathy in calves
  • A variety of clinical diseases

Pregunta 38

Pregunta
What is the most important viral cause of abortion in horses worldwide?
Respuesta
  • Equine herpesvirus 1
  • Equine herpesvirus 4
  • Bovine herpes virus 1
  • Equine sarcoid virus
  • African horse sickness

Pregunta 39

Pregunta
When do abortions usually occur in EHV 1?
Respuesta
  • Usually late gestation
  • Usually early gestation
  • Usually mid gestation
  • Abortions do not usually occur

Pregunta 40

Pregunta
How can you prevent EHV1 from spreading
Respuesta
  • Small groups based on foaling date
  • Pregnant mares be kept separate from other horses
  • There is a vaccine available
  • Cull all animals with the virus

Pregunta 41

Pregunta
How long is the aborting mare infectious for?
Respuesta
  • 1‐2 days from reproductive tract and up to 2 weeks from the respiratory tract
  • 5-10 days from reproductive tract and up to 6 weeks from the respiratory tract
  • 5‐6 days from reproductive tract and up to 4 weeks from the respiratory tract

Pregunta 42

Pregunta
How can EHV1 and EHV4 be differentiated?
Respuesta
  • ELISA test for antibody
  • Electron microscopy
  • Viral culture

Pregunta 43

Pregunta
Which age group of horses show the most severe clinical signs to EHV4
Respuesta
  • Weanling and yearlings (juveniles)
  • Adults
  • Old horses

Pregunta 44

Pregunta
Feline herpesvirus 1 (Feline rhinotracheitis) causes?
Respuesta
  • acute respiratory disease characterised by nasal discharge, ocular discharge, sneezing, dyspnoea and occasional oral ulcers
  • fatal meningoencephalitis in kittens thought to be due to direct neural spread from nasopharynx via trigeminal nerve
  • abortion of kittens during late gestation
  • generalised skin lesions. Nodules & necrosis of the superficial epidermis

Pregunta 45

Pregunta
Gallid herpesvirus 1 is also known as?
Respuesta
  • Infectious laryngotracheitis
  • Gallid rhinopneumonitis
  • Gallid encephalitis virus
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