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Fundamentals Tutorial Week 5
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- 1Unique characteristic of sympathetic nervous system is that:It uses both noradrenaline and acetylcholine as neurotransmitters
- 2Acetylcholine is synthesised from:Acetyl-CoA and choline
- 3Which cholinergic neurone will have voltage-gated calcium channels at the synapse?Pre-synaptic neuron
- 4What is the main function of Acetylcholine esterase?To degrade acetylcholine – end product is acetic acid and choline
- 5Why is atropine an antidote for nerveIt has anticholinergic effects
- 6What is the function of calcium in presynaptic nerve at the synapse?To participate in neurotransmitter release from presynaptic nerves (acetylcholine)
- 7What happens in stage 3 at a cholinergic synapse?Acetylcholine diffuses across the synaptic cleft and binds to receptors at the post synaptic nerve
- 8Which neurotransmitter is used at the neuromuscular junction?Acetylcholine
- 9Indirect-acting cholinergic drugs are:cholinergic drugs:
Agonists of acetylcholine receptors (to PNS) - 10Neostigmine is:Reversible acetylcholine esterase inhibitor
- 11Which of these is NOT a cholinergic drug effect? 1. Sweating inhibition – drying effect 2. Lacrimation 3. Urinary incontinence 4. Diarrhoea1 - sweating.
cholinergic drugs have a 'wetting' effect - 12Pancuronium is:Non-depolarizing neuromuscular blocker [competitive blocker]
- 13Parasympathomimetics are drugs that:acts like acetylcholine; activates parasympathetic nervous transmission
- 14Opening of the eye pupil could be achieved by:Parasympatholytics and Sympathomimetics
- 15Organophosphates are potent:indirect acting parasympathomimetics
- 16Myasthenia gravis is caused byInactivation of nicotinic receptors
- 17Hyoscine is most similar to: Neostigmine Atropine Pancuronium (muscle relaxant -> anti cholinergic -> targets neuromuscular junction)anticholinergic
Atropine – targets muscularanic targets - 18Overdose of neostigmine could be treated with: 1. Pilocarpine 2. Neostigmine 3. Atropine 4. PancuroniumAtropine
- 19Major suxamethonium effect is:Muscle relaxation
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- (Tutorial Questions) pharmacology Fichas sobre Fundamentals Tutorial Week 5, creado por Amelia Claire el 27/03/2017.
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- Amelia Claire
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