DNA replication sequence

Diapositiva 1

• 1. DNA Helicase unzips double helix resulting in a leading strand and a lagging strand.

LEADING STRAND

• 1. RNA primase used as primer at start of sequence.
• 2. DNA polymerase matches complimentary free nucleotides to bases.
• 3. Replaicated

LAGGING STRAND

• 1. RNA primase lays down primer for DNA polymerase.
• 2. Works backwards in Okazaki fragments of 1000-2000 bases.
• 3. Free nucleotides matched with complimentary bases on lagging strand by DNA polymerase.
• 4. Different DNA polymerase goes over primer.
• 5. Strands held together by Ligase.