Respiratory System

Description

General physiology of the respiratory system with some veterinary related questions as well.
Reem E
Flashcards by Reem E, updated 5 months ago
Reem E
Created by Reem E 5 months ago
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Question Answer
What are the functions of the Respiratory System? 1- Gas Exchange 2- Regulation of blood PH 3- Olfaction 4- Voice Production 5- Protection
Name the 2 zones at which we can classify the respiratory system regions with: 1- Conducting Zone 2- Respiratory Zones
Which zone forms the Anatomical Dead Space? The conducting zone
Which zone has the Alveolar Type 1 and Type 2 epithelial cells? The respiratory zone
Functions and characteristics of Type 1 and Type 2 Cells: -Type 1 is flat found on the surface of the alveoli. Their basement membrane is fused with the capillary endothelium (Helps facilitate gas exchange and create the Blood-Gas barrier). Has thin cytoplasm (Helps Facilitate Gas exchange) -Type 2 is found in the corner and it secretes Surfactant and aids in the regeneration of the cells by differentiation.
What are surfactants? A mix of phospholipids and proteins. It decreases the shorter the breaths are
Explain Surface Tension in the alveoli and it's relation with surfactants: Surface tension in the lung is created due to the air found inside the alveoli and the water layer found on the surface of the alveolar cells. It helps prevent stretching however it can make the lung collapse on itself. Surfactants are secretions lowering the water cohesive forces lowering the surface tension.
*A syndrome where type 2 cells are immature in premature newborns and unable to produce surfactants? Respiratory Distress syndrome
Define the 2 types of Pulmonary-Blood Circulation 1- Pulmonary Circulation(Gas Exchange and Oxygenation) 2- Bronchial Circulation(Arising from aorta to nourish the lungs)
The mechanism of respiration and explain them: 1- Pulmonary Ventilation 2- External Respiration (1+2= Pulmonary circulation) 3- Gas Transport 4- Internal Respiration 5- Cellular Respiration (4+5= Systemic Circulation) you do the explanation lol <3
The Mechanics of Respiration:
Lung volume and capacities: 4 and 4
Alveolar Ventilation: 1- Minute Ventilation(6000ml/min)(Not very accurate due to the fact that anatomical dead space exists) 2- Alveolar Ventilation (4200) Eupnea (5100) Hyperpnea (2400) Polypnea (0) Apnea
What is the Physiological Dead Space? Anatomical Dead Space + Functional(Alveolar) Dead Space
Layers Forming the Blood-Gas Barrier 1-Surfactant 2-Epethelial cells of the alveoli 3-Basment membrane of the ep. cells 4-Interstitum 5-Basment membrane of the capillaries 6-Endothelial cells of the capillaries 7-Plasma 8-Membrane of Erythrocytes (RBC touch the capillary wall to prevent gasses from traveling through the plasma)
4 Factors determining the rapid gas exchange: 1- Surface area of alveoli 2- Thickness of alveolar wall 3- Partial pressure between 2 sides of the membranes 4- Diffusion Co-efficient
Ways of O2 transportations in body: 1- Through Oxyhemoglobin 2- Dissolved in plasma
The 4 factors affecting the unloading of O2: 1- The Bohr Effect 2- The Carbamino Effect 3- DGP Levels 4- Temperatures
Ways of CO2 transportation: 1- Carbaminohemoglobin 30% 2- As Carbonic Acid 60% 3- Amino Acids in Plasma 10%
How can O2 be delivered efficiently in fetus? Through Fetal Hb. It has a higher affinity to O2 allowing it to pass through the placenta
Components involved in the neural control of respiration: 1- DRG: Control Spinal Motor N. 2- Apneustic: Controls DRG rate 3- Pneumotaxic Center: Inhibits apneustic center 4- Pulmonary Stretch Receptors: Hering-Breuer Reflex * All can be controlled by a higher voluntary center in Cortex
1- Which chemoreceptors control the PO2 2- Which ones control PCO2 1- Peripheral receptors 2- Central receptors- Depends on H levels in body
Name the 3 methods as to how unwanted substances can settle in the respiratory tract: 1- Sedimentation(Gravitational Pull) 2- Inertia 3- Brownian movement
Ways of Respiratory Clearance: 1- Upper respiratory clearance through mucosal secretions by the exocrine cells moving foreign substances cranially 2-Alveolar clearance through Macrophages, Lymph nodes or Isolation *Asbestosis, Silicosis and Anthracosis
Non-Respiratory Functions of the Respiratory System: Panting and Purring
Describe Panting -Prevalent in many species, dogs included. Allows an increases in the volume of the anatomical dead space which allows further evaporation of the water from the mucosal membranes in such regions. -Done for thermoregulation
The 3 Patterns of Panting 1- Inhalation and exhalation through nose 2- Inhalation through nose and exhalation through nose and mouth 3- Inhalation and exhalation through both nose and mouth 2nd and 3rd are most effective
Generally, how many air sacs are found in domestic birds? 9 air sacs. 5 Cranial sacs(2 Cervical, 2 Thoracic, 1 Calicular) and 4 Caudal sacs (2 Thoracic and 2 Abdominal)
Avian comparative points 1- Syrinx: The vocal organ replacing the pharynx 2- Complete Tracheal rings 3- Lungs attached to the ribs and not able to expand 4- Birds have no diaphragm thus lacking the Abdominal-Thoracic separation
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