Flashcards
Red Blood cells
Cards in this deck (28)
- 1The cellular components of blood are known as the......formed elements of blood
- 2These include?Red blood cells
White blood cells
Platelets (cell fragments
involved in blood clotting) - 3Red Blood Cells account for what percentage of the total blood volume?45%
- 4In females, the figure is?around 41%
- 5This value is known as the?HAEMATOCRIT
(blood count) - 61 microlitre (1µl) of blood (i.e. 1mm3 of blood) contains:5 million RBCs in males
~4.5million RBCs in females - 7Total blood volume is around?5 litres
- 8Red blood cells are flattened, biconcave discs. They are....um in diameter and....um thick.7 and 2
- 9The function of RBCs is?to transport gases in the circulation
Oxygen (O2)
Carbon Dioxide (CO2) - 10RBCs have to squeeze through capillaries, so are easily.......deformable.
- 11Transport of gases is provided by the presence of ................. inside the RBCsHAEMOGLOBIN
- 12Each RBC contains around............. molecules of Hb280 million
- 13Hb is a........molecule.pigment(gives RBCs their colour)
- 14There are TWO main parts to the Hb molecule:(i) Protein part (globin)
pigment part (haem; heme) - 15Which part contains Iron?Haem (pigment part)
- 16The haem part carries which gas?Oxygen
- 17The concentration of Hb in the blood is about .....g/litre150g
- 18RBCs have few cell organelles. The don't possess?Nucleus
Mitochondria - 19No mitochondria means?therefore they
obtain energy
ANAEROBICALLY
(without oxygen) - 20RBCs have a.....life span.short
- 21About ...% of the total number of RBCs is destroyed every day1
- 22The destruction of RBCs occurs in the?spleen and by phagocytic cells in
the circulation - 23RBC synthesis occurs in the ?BONE MARROW
- 24In adults , the synthesis occurs in the bone marrow found in?bones of chest (e.g. sternum)
base of skull
long bones in arms & legs - 25large bone marrow cells (stem cells) which DO possess a nucleus go through several cell stages, gradually lose the nucleus and become?Mature RBCs.
- 26The whole process is under the control of which hormone?ERYTHROPOIETIN
(EPO) - 27What percentage of EPO comes from the kidneys and what percentage comes from the liver?90% and 10%
Normal circulating levels of EPO maintain
the normal rate of RBC synthesis - 28In situations where there is a decreased level of O2, such as haemorrhage, decreased cardiac efficiency high altitude this stimulates the production of?EPO
therefore stimulates production of extra RBCs
therefore increases the oxygen-carrying capacity
of the blood
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- University Pod Year 1 Flashcards on Red Blood cells, created by Morgan Morgan on 06/02/2014.
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- Morgan Morgan
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