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Sulphonamides

Description

Year 2 Flashcards on Sulphonamides, created by gina_evans0312 on 16/04/2014.

Flashcards by gina_evans0312, updated more than 1 year ago

	Created by gina_evans0312 about 10 years ago

208

Resource summary

Question	Answer
Antibiotic Class	Class 2 (Substrates for Macromolecule Production)
Target (System)	Folic acid synthesis
Requirement of Target	Required to make DNA
Selective Toxicity	Humans get folic acid from the diet, bacteria use PABA to make it
Main Target (Enzyme)	Dihydropterase Synthase, which are inhibited by Sulphinomides
Dihydrofolate Reductase	Present in human cells but structured differently
Drug for Dihydrofolate Reductase	Trimethoprim

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