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Description
Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
about 10 years ago
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| Question | Answer |
| Th1- Polarising Cytokine | IL12 |
| Th1- Polarising Infection | Viral/intracellular pathogens |
| Th1- Type of Immunity | Cell Mediated |
| Th1- Other Cells Mediated | Tc to destroy infected cells, macrophages for phagocytosis |
| Th1- B- Cells | Activation, so they produced Ig for macrophage activation |
| Th1- Cytokines Produced | Il2, IFN-Gamma & TNF-Beta |
| Th2- Polarising Cytokine | IL4 |
| Th2- Polarising Infection | Bacterial/extracellular |
| Th2- Type Of Immunity | Humoral |
| Th2- Other Cells Mediated | Macrophages- inhibited, Eosinophils- activated (kills IgE coated bact) Mast Cells- activated (IgE mediated degranulation) |
| Th2- B Cells | Activation to produce IgE |
| Th2- Cytokines Produced | IL4, 5, 6 & 10, TGF-Beta |
| Treg Cells- Role | Reduce effector mediateed immunity by CD4 & 8, and reduces Antigen presentation (stops immune response going overboard) |
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