Influenza Drugs

Question	Answer
Adamentiamine	Prevents HA from unfolding & causing vesicle fusion (trapping the virus in the endosome)
NA Inhibitors	Reduces length & severity of symptoms
NA Inhibitor Effect	80% effective when given prophylactically
NA Inhibitor Administration	Given early in infection, taken over 5 days
RNA Metabolism Inhibitors	A non-specific nucleotide analogue that binds to RNA producing enzymes
RNA Metabolism Inhibitors (Adverse Effects)	Can't be given for too long, toxic
RNA Metabolism Inhibitors (Other Targets)	Cellular enzymes
RNA Polymerase Inhibitors	Prevent production of viral RNA
siRNA	Degrades mRNA
Anti-M2 (i.e. Amantadine)	Prevents RNA from exiting the virion (though some stages are resistant)

Resource summary

	Created by gina_evans0312 about 10 years ago