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Description
Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
about 10 years ago
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| Question | Answer |
| FAS | Fluorescent Antibody Staining |
| FAS Target- Target | Treponema pallidum subspecies pallidum antigens |
| FAS Target- Technique | Prepare smear and add specific Ig tagged with dye, wash off unbound Ig and put under fluor. microscope |
| FAS Target- Difficulties | Bacteria cannot be transported, so expensive equipment is needed at the clinic |
| RPR (Non-Specific) Test | Rapid Plasma Reagin (Non Specific) Test |
| RPR (Non-Specific) Test- Target | Ig for lipids released by infected cells |
| RPR (Non-Specific) Test- Technique | Cardiolipid (Ag) on carbon particles are mixed with serum- clumping = infection |
| RPR (Non-Specific) Test- Issues | High False +ve rate |
| TPHA (Specific) Test | Treponema pallidum Haemoaggluntenin (HA) test |
| TPHA (Specific) Test- Target | T.p HA Ig produced by body |
| TPHA (Specific) Test- Technique | RBCs are coated with Ag and mixed with serum- diffuse pattern = positive result |
| TPHA (Specific) Test- Issues | Expensive (but specific) |
| Treatment | Benzathine Penicillin (for partners as well) |
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