767457
Description
Flashcards by gina_evans0312, updated more than 1 year ago
|
Created by gina_evans0312
about 10 years ago
|
|
| Question | Answer |
| Main Methods of Treatment | Inhalation- gets drugs where needed but limits drugs possible |
| 'Treaters' | Bronchodilators |
| Beta-2 Agonists | Used to cause bronchodilation |
| SABA | Short acting beta agonists- act in mins, last 3-5 hours |
| SABA Example | Salbutamol |
| LABAs | Long Acting Beta Agonists- delayed onset, last 12 hours |
| LABAs Example | Salmeterol |
| Beta Agonist Side Effects | Tremors, palpitations, headache & nervous tension (they can stimulate B1 receptors) |
| Theophylline- Effect | Non selective phosphodiesterase inhibition, inc in cAMP and bronchodilation |
| Theophylline- Theraputic range | Narrow |
| Theophylline- Side Effects | Tremor, nausea, insomnia |
| Theophylline- Toxicity | Cardiac arrythmias, convulsions |
| Theophylline- Metabolism | CYP450- so any drugs that inhibit metabolising enzymes will inc theophylline levels |
| Antimuscarinics- Effect | Block Ach stimulation of smooth muscle |
| Antimuscarinics- Ipratropium (Effect) | Short acting muscarinic that binds non selectively |
| Antimuscarinics- Ipratropium (Administration) | Water soluble, little enters circulation |
| Antimuscarinics- Ipratropium (Timing) | Slow peak of action (30 mins) lasts 3-6 hours |
| Antimuscarinics- Ipratropium (Side Effects) | Dry mouth, throat irritation, blurred vision |
Want to create your own Flashcards for free with GoConqr? Learn more.