Asthma Treatment (Long Term)

Question	Answer
Corticosteroids- Example	Budenoside
Inhaled Corticosteroids- Effect	Red. airway inflammation by red. inflammatory cell infiltration, and odema by acting on vascular endothelium
Inhaled Corticosteroids- Times	Long term prophylaxis- 3 to 7 days for full effect
Inhaled Corticosteroids- Side Effects	Hoarseness and thrush of mouth/throat
Oral Corticosteroids- Role	Reserved for severe, acute attacks- single dose daily for 5 days
Oral Corticosteroids- Side Effects	Peptic ulceration, osteoporosis, cateracts, links to diabetes
Cromones- Effect	Block mast cells by blocking Cl- channels, prevent mediator secretion
Cromones- Use	No longer widely used (useless in acute attacks) but good prophylaxis for allergy associated attacks
Cromones- Time	Short duration- take 4x a day
Cromones- Side Effects	Few- generally well tolerated
Leukotrine Receptor Agonists- Effect	Prevent activation of leukotrine receptors that cause early phase bronchospasm and late phase inflammation
Leukotrine Receptor Agonists- Montelukast (Effect)	Selective receptor of LTC4, LTD4 & E4 leading to bronchodilation and red. inflammation
Leukotrine Receptor Agonists- Montelukast (Role)	Used for prophylaxis of mild to moderate asthma, especially during exercise/at night
Leukotrine Receptor Agonists- Montelukast (Side Effects)	Well tolerated, not really any
Leukotrine Receptor Agonists- Montelukast (Steroid Phobia)	Useful for steroid phobics or those with allergy related conditions

Resource summary

	Created by gina_evans0312 about 10 years ago