767595
Description
Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
about 10 years ago
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| Question | Answer |
| Location | Secondary Lymphoid organs |
| Maturation | Antigen independent |
| Activation | Ag dependent, relies on Th cells |
| Thymus (Th Cell) Independent Ags- Immunity Type | Contributes to innate immunity |
| Thymus (Th Cell) Independent Ags- Response type | Weaker, quicker response with no class switch |
| Thymus (Th Cell) Independent Ags- Memory Cells | No memory cell formation |
| Thymus (Th Cell) Independent Ags- Somatic Mutation | None |
| Thymus (Th Cell) Independent Ags- Ag Type | Thymus independent Ag tend to be highly repetitive i.e. DNA, flagellin, and crosslink repeatedly with BCR |
| Thymus (Th Cell) Independent Ags- Dominant Ig Secreted | IgM- For opsonisation, assisting compliment and agglutination |
| Thymus (Th Cell) Dependent Ags- Immune Type | Adaptive Immunity |
| Thymus (Th Cell) Dependent Ags- Linked Recognition | B and Th cells recognise epitopes of the same antigen |
| Thymus (Th Cell) Dependent Ags- Linked B-Cell Ag Presentation | B cells bound to their specific antigen are 10000x better at presenting the epitopes of that antigen than an unbound B cell |
| Thymus (Th Cell) Dependent Ags- Germinal Centre Response | Only Thymus dependent Ag's can induce a germinal centre response |
| Thymus (Th Cell) Dependent Ags- Th Cells | Th cells can recognise AN epitode of the antigen presented by the B cell, not necessarily the same one as the B cell used to activate itself |
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