Created by gina_evans0312
about 10 years ago
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Question | Answer |
What the fuck is it? | A common pathological condition where the body fails to properly respond to insulin |
Area of Effect | Skeletal muscle |
Associated With | Obesity and chronically high blood FAs |
Mechanism- White Adipose Tissue | WAT acts as an endocrine organ, screting IL6, leptin, resistin and other adipokines that alter body responses to insulin |
Proposed Mechanism of Action- PKC | Adipokines P IRS1 on the serine residue, preventing P on the tyrosine residue, and it's role as a signal transducer to insulin |
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