806507
Description
Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
about 10 years ago
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| Question | Answer |
| Monoamine Oxidase Inhibitors- Effect | Antidepressants |
| Monoamine Oxidase Inhibitors- Method of Action | Increase of NA, DA and 5-Hydroxy tyrosine concentrations |
| Monoamine Oxidase Inhibitors- Side Effects | Tyramine accumulation leads to inc blood pressure (dangerous to cranial blood vessels) |
| Tricyclic Antidepressants- Effect | Antidepressents/mood elevators |
| Tricyclic Antidepressants- Method of Action | Red. Uptake 1 system in presynaptic neurone, increasing synaptic levels/postsynaptic stimulation |
| Amphetamines- Effect (Uptake System 1) | Competes with NA for reuptake by US1, so NA conc in the synapse increases |
| Amphetamines- Effect (Vesicles) | Once in the cell, it concentrates in the vesicles, displacing NA into the cytoplasm |
| Amphetamines- Effect (Monoamine Oxidase) | Blocks MOA so CAs in the cytoplasm build up and leak out into the synapse through the US1 |
| Amphetamines- Effect (Agonist) | Works as an agonist of posy synaptic cell receptors |
| Amphetamines- Overall Effect | Overstimulation of postsynaptic neurones |
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