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Flashcards

L4. CT Types

B M Histology 2 Year English 11 cards

Cards in this deck (11)

  1. 1What types of embryonic CT are there? List them1. Mesenchyme
    2. Mucoid
  2. 2Describe mesenchymeLoose spongy tissue
    Packing between developing structures of embryo
    Contains mesenchymal cells that are multipotent - can give rise to any adult CT
  3. 3Describe mucoidLoose CT found in parts of embryo especially in Wharton's jelly
    Has large stellate-shaped fibroblasts
  4. 4What type of special forms of CT are there? List them1. Adipose tissue (brown and white)
    2. Cartilage
  5. 5What type of cells are involved in the production of cartilage?1. Chondrogenic cells: derived from mesenchymal cells. Differentiate into chondroblasts and osteoprogenitor cells
    2. Chondroblasts: derived from 2 sources - msesenchymal cells (centre of chondrofication), chondrogenic cells (inner cellular layer of perichondrium)
    3. Chondrocytes: chondroblasts surrounded by matrix. Can resume active protein synthesis if they revert back to chondroblasts.
  6. 6Describe cartilagenous matrixComponents: collagen, proteoglycans, hyaluronic acid
    Has two regions:
    1. Territorial matrix
    2. Interterritorial matrix
  7. 7What are the two regions of cartilagenous matrix? Give brief description1. Territorial matrix: around each lacuna/isogenous group
    2. Interterritorial matrix: bulk of matrix, rich in type II collagen, low in proteoglycans
  8. 8What is the perichondrium? Give a brief description of how it is formed, and what it is composed ofMesenchymal cells at periphery of cartilage form fibroblasts
    Fibroblasts form perichondrium in 2 layers:
    1. Inner cellular region (chondrogenic) - Cells which differentiate into chondroblasts
    2. Outer fibrous region (elastic, collagen, fibroblasts and blood vessels). Chondroblasts pushed out due to inner growth
    Vascular.
    Articular surfaces/joints have no perichondrium, rely on synovial fluid for nutrients
  9. 9How is cartilage formed?Differentiation of mesenchymal cells to form chondroblasts
    Produces ground substance and fibrous extracellular material
    Extracellular material traps chondroblast in lacuna
    Chondroblast undergoes mitotic divisions to form chondrocyte clusters (isogenous group)
  10. 10What types of cartilage growth are there?1. Interstitial growth: proliferation of chondrocytes to expand cartilage from within. Lengthens bone. Articular cartilage doesn't have perichondrium, therefore only grows by interstitial growth
    2. Appositional growth: Growth at periphery; chondrogenic cells in perichondrium differentiate into chondroblasts. Forms new layer of cartilage around existing layers. Increases width.
  11. 11What types of cartilage are there?1. Hyaline: most common. Mostly type II collagen and chondrocytes. Found in larynx, epiphyseal/growth plates in growing bones
    2. Elastic: Hyaline but contains elastic fibres between collagen bundles. Grows by apposition. Found where support with flexibility is required e.g. epiglottis, auditory tube
    3. Fibrocartilage: transition between dense CT and hyaline cartilage. Matrix consists of chondrocytes within lacunae. Does not possess perichondrium. Found where support and tensile strength needed e.g. intervertebral discs, menisci

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2 Year Histology Flashcards on L4. CT Types, created by B M on 18/06/2017.
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