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Chapter 7 - The Blue Print of Life, from DNA to Protein

Dorothy B

Adaptive Immunity (ONLY Lecture 15 Part 2)

Description

Adaptive Immunity will be in shades of red. Anything associated with innate immunity is in shades of blue. Lecture 16 is more in depth.

Mind Map by GraceEChem, updated more than 1 year ago

	Created by GraceEChem over 10 years ago

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Resource summary

Adaptive Immunity (ONLY Lecture 15 Part 2)

Humoral Immunity
1. "Antibody-mediated"
2. B-cell based
Cellular Immunity
1. "Cell-mediated"
2. T-cell based
Types
1. Naturally acquired active
  1. Getting sick
  2. B memory cells
2. Nat. acq. passive
  1. Transfer (mother's milk)
3. Artificially acq. active
  1. Vaccination
4. Art. acq. passive
  1. Antibodies from one host intro to another
Antigens
1. Epitopes
  1. Reaction sites on antigens for specific antibody or T cell receptor
2. Affinity
  1. Binding strength at just ONE site
3. Avidity
  1. Overall antigen-binding at ALL sites
Major Histocompatibility Complex (MHC)
1. Genes code for self/nonself
2. In humans "Human Leukocyte Antigen" (HLA)
3. Three Classes
  1. CLASS I
    1. All types
    2. Important for organ transplant
  2. CLASS II
    1. Antigen-presenting cells
    2. Important for T-cell communications
      1. Macrophages
      2. Dendritic cells
      3. B cells
  3. CLASS III
    1. Secreted proteins
    2. Nonself/self recognition
4. Class I and II Structures
  1. Heterodimers of alpha & beta subunits

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