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374208
Hereditary WBC Disorders
Description
Mind Map on Hereditary WBC Disorders, created by KevinShirley on 20/11/2013.
Mind Map by
KevinShirley
, updated more than 1 year ago
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Created by
KevinShirley
almost 11 years ago
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Resource summary
Hereditary WBC Disorders
May-Hegglin Anomaly
Associated Conditions
Annotations:
Abnormal bleeding may be present in some individuals.
thrombocytopenia
giant platelets
WBC's affected
neutrophils
appearance
Döhle-like bodies
Annotations:
Rod shaped inclusions at the edge of the cytoplasm. They are like Döhle bodies but larger.
prevalence
unknown
Alder-Reilly Anomaly
Associated Conditions
dwarfism
gargoylism
WBC's affected
All cell lines
hallmark feature
Appearance
coarse dark granulation
prevalence
rare
Pelger-Huet Anomaly
prevalence
common
associated conditions
leukemias
myleoproliferative disorders
severe infections
WBC's affected
segmented neutrophils
appearance
hyposegmentation of nucleus
heterozygotes
peanut-shaped
dumbbell-shaped
pince-nez-shaped
homozygotes
spherical non-lobed
Chediak-Higashi Syndrome
prevalence
rare
associated conditions
neutropenia
albinism
photophobia
recurrent staphylococcus infections
WBC's affected
neutrophils (mostly)
lymphocytes
monocytes
appearance
giant purple-gray granules
Media attachments
Alders_anomaly (image/jpg)
chediak_higashi_syndrome (image/jpg)
May-Hegglin (image/jpeg)
pelger-huet_anomaly (image/jpg)
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