Glycan Structure & Complexity

Judith Yan
Mind Map by Judith Yan, updated more than 1 year ago
Judith Yan
Created by Judith Yan about 5 years ago
3
0

Description

review chart

Resource summary

Glycan Structure & Complexity
1 related fields
1.1 genomics
1.1.1 gene sequence
1.2 proteomics
1.2.1 proteins
1.2.1.1 post-translational modification
1.2.2 peptides
1.3 glycomics
1.3.1 cell glycans
2 Locations in the cell?
2.1 membrane-associated glycoforms
2.1.1 classifications
2.1.1.1 glycolipids
2.1.1.1.1 glycan functions in the ectodomain
2.1.1.1.2 linkage
2.1.1.1.2.1 glucose -- ceramide
2.1.1.2 glycoproteins
2.1.1.2.1 polypeptide
2.1.1.2.1.1 ectodomain
2.1.1.2.1.2 cytoplasmic domain
2.1.1.2.2 covalent linkage
2.1.1.2.2.1 N - asp
2.1.1.2.2.2 O - Ser/Thr
2.1.1.2.3 glycan functions in the ectodomain
2.1.1.3 proteoglycans
2.1.1.3.1 long glycan part
2.1.1.3.2 lots of SO4-
2.1.1.3.2.1 prevents collapsing
2.1.1.3.3 examples
2.1.1.3.3.1 syndecans
2.1.1.3.3.2 glypicans
2.1.1.3.3.3 CD44
2.1.1.3.4 in extracellular matrix:
2.1.1.3.4.1 aggrecan/versican
2.1.1.3.4.1.1 "test-tube brush"
2.1.1.3.4.2 glycosaminoglycans
2.1.1.3.4.2.1 hyaluronan
2.1.1.3.4.2.2 DRU + tetrasaccharide - ser
2.1.2 lectin-saccharide interactions
2.1.2.1 cell-cell interactions
2.1.2.1.1 recognition
2.1.2.1.1.1 by viral proteins
2.1.2.1.1.2 cell-cell
2.1.2.1.1.3 by bacteria
2.1.2.1.2 adhesion
2.1.2.1.2.1 epithelial layer formation
2.1.2.1.3 binding of toxins...?
2.1.2.2 strength
2.1.2.2.1 weaker than antigen-antibody
2.1.2.3 functions
2.1.2.3.1 fertilization
2.1.2.3.2 immunity
2.1.2.3.3 infection
2.1.2.3.4 cancer
2.1.3 synthesis
2.1.3.1 quality-control
2.1.3.1.1 addition of glycan
2.1.3.1.1.1 Golgi apparatus
2.1.3.1.2 sorting
2.1.3.1.2.1 ER
2.1.3.2 extocytosis
2.1.4 examples
2.1.4.1 blood group glycoprotein
2.1.4.1.1 tetrasaccharide
2.1.4.1.1.1 has fifth sugar: A/B
2.1.4.1.1.2 no fifth sugar: O
2.2 intracellular
2.2.1 storage glycoforms
2.2.1.1 starch (plants)
2.2.1.1.1 amylopectin
2.2.1.1.1.1 amylose
2.2.1.1.1.1.1 a-1,4 linear
2.2.1.1.1.2 a-1,4 / 1,6
2.2.1.2 glycogen (animals)
2.2.1.2.1 a-1,4 / 1,6
2.2.1.2.2 many nonreducing ends
2.2.1.2.3 digestion
2.2.1.2.3.1 intracellular
2.2.1.2.3.1.1 glycogen phosphorylase
2.2.1.2.3.1.1.1 releases glc-1-phosphate
2.2.1.2.3.1.2 debranching enzymes
2.2.1.2.3.2 extracellular
2.2.1.2.3.2.1 alpha amylase
2.2.1.2.3.2.1.1 random attacks alpha-1,4
2.2.1.3 insoluble
3 glucose metabolism
3.1 glucose from diet
3.1.1 amylase action
3.1.1.1 gut lumen
3.1.1.1.1 intestinal absorption
3.1.1.1.1.1 hepatic portal vein
3.1.1.1.1.1.1 hepatocytes
3.1.1.1.1.1.1.1 glycolysis
3.1.1.1.1.1.1.1.1 ATP
3.1.1.1.1.1.1.2 glycogenesis
3.1.1.1.1.1.1.2.1 glycogen
3.2 glycogen from liver/myocyte
3.2.1 glycogen phosphorylase
3.2.1.1 glc-1-phosphate
3.2.1.1.1 glc-6-phosphate
3.2.1.1.1.1 glycolysis
3.2.1.1.1.1.1 ...
Show full summary Hide full summary

Similar

Carbohydrates
kevinlinkovoor
DNA Basics
Sarah Juliette B
DNA (labeling) for biochem and cell biology (lecture 2)
MrSujg
Сells and development lecture 1 +organelles
MrSujg
DNA questions not from the lectures
MrSujg
Carbohydrates, Metabolism & spectrometry
tanitia.dooley
Energy Metabolism
hanngeiss
Protein section 1
MrSujg
Cell Lecture 3
MrSujg
Protein section 5
MrSujg
Protein section 3
MrSujg