Neurotransmission and Second Messengers

snlogel
Mind Map by snlogel, updated more than 1 year ago
snlogel
Created by snlogel about 6 years ago
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Neurotransmission and Second Messengers
1 Calcium
1.1 Release vesicles
1.2 Muscle contraction
1.3 Regulating blood flow
1.4 Platelet functioning
1.5 Activation of the clotting cascade
2 Metabolism of NE
2.1 Catechol-O-methyl transferase (COMT)
2.2 Monamine oxidase (MAO)
3 Noradrenergic receptors
3.1 Alpha 1: vascular smooth muscle contraction (vasoconstriction)
3.2 Alpha 2
3.2.1 Inhibit NE release
3.2.2 Inhibit NE-mediated vasoconstriction
3.3 Beta 1
3.3.1 Increase heart rate
3.3.2 Increased myocardial contractility
3.4 Beta 2
3.4.1 Vasodilation
3.4.2 Bronchodilation
4 Muscarinic receptors
4.1 M1
4.1.1 Enteric nervous system
4.1.2 Rest and digest
4.2 M2: decrease contractility and heart rate in the atria at the SA node
4.3 M3
4.3.1 Increase bladder contraction
4.3.2 Increase gut peristalsis
4.3.3 Lacrimation or tearing
4.3.4 Miosis
4.3.5 Bronchoconstriction
5 Dopamine receptors
5.1 D1: relax renal vascular smooth muscle
5.2 D2: found in the brain
6 Histamine receptors
6.1 H1
6.1.1 Allergy symptoms
6.1.2 Pruritus
6.1.3 Bronchoconstriction
6.2 H2: increase gastric acid secretion
7 ADH receptors
7.1 V1: increase vascular smooth muscle contraction
7.2 V2: increase reabsorption in collecting tubules of the kidney
8 G-protein second messengers
8.1 Alpha: Epi and NE
8.2 Beta: Epi and NE
8.3 M: ACh
8.4 D1, D2: dopamine
8.5 H1, H2: histamine
8.6 V1, V2: vasopressin
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