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Liver Pathology

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Notes from Doctors in Training
snlogel
Mind Map by snlogel, updated more than 1 year ago
snlogel
Created by snlogel over 10 years ago
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Resource summary

Liver Pathology
  1. Budd-Chiari syndrome
    1. Obstruction of IVC
      1. Obstruction of hepatic veins
        1. Absence of JVD
          1. Congestion of liver
          2. Reye's syndrome
            1. Children
              1. Aspirin
                1. Viral infection
                  1. Hepatoencephalopathy
                  2. Wilson disease: copper accumulation
                    1. Organs
                      1. Liver
                        1. Brain
                          1. Cornea
                            1. Kidneys
                              1. Joints
                              2. Symptoms
                                1. Cirrhosis
                                  1. Corneal deposits called Kayser-Fleischer ring
                                    1. Hepatocellular carcinoma
                                      1. Hemolytic anemia
                                        1. Basal ganglia degeneration
                                          1. Parkinsonian symptoms
                                            1. Hepatoencephalopathy
                                              1. Dementia
                                                1. Fanconi's syndrome: proximal tubule dysfunction
                                                2. Treatment: penicillamine
                                                3. Hemochromatosis (bronze diabetes)
                                                  1. Cirrhosis
                                                    1. Diabetes mellitus
                                                      1. Skin pigmentation
                                                        1. Primary: AR disorder
                                                          1. Secondary: transfusions (chronic)
                                                            1. Treatment
                                                              1. Phlebotomy
                                                                1. Deferoxamine
                                                              2. Alpha 1-antitrypsin deficiency
                                                                1. Early onset emphysema (panacinar)
                                                                  1. Cirrhosis
                                                                    1. Jaundice
                                                                      1. Elevated LFTs
                                                                    2. Hepatocellular carcinoma
                                                                      1. Increased risk
                                                                        1. Hepatitis B, C
                                                                          1. Wilson disease
                                                                            1. Hemochromatosis
                                                                              1. Alpha 1-antitrypsin deficiency
                                                                                1. Alcoholic cirrhosis
                                                                                  1. Carcinogen exposure
                                                                                  2. Serum marker: alpha-fetoprotein
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