Liver Pathology

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Mind Map by snlogel, updated more than 1 year ago
snlogel
Created by snlogel about 6 years ago
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Liver Pathology
1 Budd-Chiari syndrome
1.1 Obstruction of IVC
1.2 Obstruction of hepatic veins
1.3 Absence of JVD
1.4 Congestion of liver
2 Reye's syndrome
2.1 Children
2.2 Aspirin
2.3 Viral infection
2.4 Hepatoencephalopathy
3 Wilson disease: copper accumulation
3.1 Organs
3.1.1 Liver
3.1.2 Brain
3.1.3 Cornea
3.1.4 Kidneys
3.1.5 Joints
3.2 Symptoms
3.2.1 Cirrhosis
3.2.2 Corneal deposits called Kayser-Fleischer ring
3.2.3 Hepatocellular carcinoma
3.2.4 Hemolytic anemia
3.2.5 Basal ganglia degeneration
3.2.6 Parkinsonian symptoms
3.2.7 Hepatoencephalopathy
3.2.8 Dementia
3.2.9 Fanconi's syndrome: proximal tubule dysfunction
3.3 Treatment: penicillamine
4 Hemochromatosis (bronze diabetes)
4.1 Cirrhosis
4.2 Diabetes mellitus
4.3 Skin pigmentation
4.4 Primary: AR disorder
4.5 Secondary: transfusions (chronic)
4.6 Treatment
4.6.1 Phlebotomy
4.6.2 Deferoxamine
5 Alpha 1-antitrypsin deficiency
5.1 Early onset emphysema (panacinar)
5.2 Cirrhosis
5.2.1 Jaundice
5.2.2 Elevated LFTs
6 Hepatocellular carcinoma
6.1 Increased risk
6.1.1 Hepatitis B, C
6.1.2 Wilson disease
6.1.3 Hemochromatosis
6.1.4 Alpha 1-antitrypsin deficiency
6.1.5 Alcoholic cirrhosis
6.1.6 Carcinogen exposure
6.2 Serum marker: alpha-fetoprotein
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