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Mind map

Drug Metabolism

snlogel Step 1 Prep English

Mind map on drug metabolism: phase I, phase II, disulfiram-like reaction and zero order kinetics

Mind map: Drug metabolism

Map content

Drug Metabolism

Phase I
- Reactions
  - Reduction
  - Oxidation
  - Hydrolysis
- Metabolites
  - Slightly polar
  - Water soluble
  - Active
Phase II
- Reactions
  - Acetylation
  - Methylation
  - Sulfation
  - Glucuronidation
- Metabolites
  - Very polar
  - Inactive
Disulfiram-like reaction
- Metronidazole
- Certain cephalosporins
- Procarbazine
- 1st generation sulfonylureas
Zero order kinetics
- Phenytoin
- Ethanol
- Aspirin
TCAs
- Imipramine
- Clomipramine
- Amitriptyline
- Nortriptyline

Information

Description: Notes from Doctors in Training
Created by: snlogel
Views: 270
Tags: step 1 prep usmle step 1
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