Drug Metabolism

snlogel
Mind Map by , created almost 6 years ago

Notes from Doctors in Training

29
0
0
Tags
snlogel
Created by snlogel almost 6 years ago
Liver Pathology
snlogel
Antidepressants
snlogel
T Cells
snlogel
A Christmas Carol - Charles Dickens
chloeprincess10
American West - Key Dates
Rachel I-J
Platelets
snlogel
Cranial Nerves
snlogel
Psychosis and Antipsychotic Drugs
snlogel
Hemolytic Anemias
snlogel
Cardiac Embryology
snlogel
Drug Metabolism
1 Phase I
1.1 Reactions
1.1.1 Reduction
1.1.2 Oxidation
1.1.3 Hydrolysis
1.2 Metabolites
1.2.1 Slightly polar
1.2.2 Water soluble
1.2.3 Active
2 Phase II
2.1 Reactions
2.1.1 Acetylation
2.1.2 Methylation
2.1.3 Sulfation
2.1.4 Glucuronidation
2.2 Metabolites
2.2.1 Very polar
2.2.2 Inactive
3 Disulfiram-like reaction
3.1 Metronidazole
3.2 Certain cephalosporins
3.3 Procarbazine
3.4 1st generation sulfonylureas
4 Zero order kinetics
4.1 Phenytoin
4.2 Ethanol
4.3 Aspirin
5 TCAs
5.1 Imipramine
5.2 Clomipramine
5.3 Amitriptyline
5.4 Nortriptyline

Media attachments