Immunology

ainbatrisyia
Mind Map by ainbatrisyia, updated more than 1 year ago
ainbatrisyia
Created by ainbatrisyia almost 4 years ago
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Immunology mind map.
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Immunology
1 Immunology is the study of immune system that includes various cells, tissues and organs, working collectively and defend against harmful pathogens, cells and substances.
2 Lines of Defences:

Annotations:

  • 1. First line  - External physical barriers  e.g skin2. Second line Internal physiological barrierse.g inflammation3. Third line- Adaptive immune response
3 Components of Immune System
3.1 Cardiovascular system

Annotations:

  • Heart and blood vessel
3.2 Mononuclear Phagocyte System

Annotations:

  • - Network of reticular fibre - Phagocytes (macrophages)
3.3 Lymphatic System
3.3.1 Primary lymphoid organ

Annotations:

  • 1. Bone marrow 2. Thymus
3.3.2 Secondary Lymphoid organs

Annotations:

  • 1. Adenoid 2. Tonsils 3. Lymph nodes 4. Spleen 5. Mucosa-Associated Lymphoid Tissue (MALT)
3.3.3 Lymph circulatory system

Annotations:

  • Lympathic vessels
4 Cells of Immune system
4.1 Leukocytes

Annotations:

  • - Have nuclei - Involved in phagocytosis, inflammation, adaptive immune response
4.2 Platelets

Annotations:

  • - Do not have nuclei - Involved in inflammation and blood clotting
4.3 Basophil

Annotations:

  • Involve in inflammation
4.4 Neutophil

Annotations:

  • Killing the invading microbes
4.5 Eosinophil

Annotations:

  • Defense against parasitic infection.
  • Involve phagocytosis
4.6 Monocytes

Annotations:

  • Involve in phagocytosis
4.7 Lymphocyte

Annotations:

  • Response to foreign invaders in the body
4.8 Mast cell

Annotations:

  • Involve in wound healing and defense against pathogen
4.9 Natural killer cells (NK cells)

Annotations:

  • Host rejection of both tumors and virally infected cells
5 Lines of Defense
5.1 Innate immune response

Annotations:

  • - Non specific - IMMUNE RESPONSE PREFORMED - Response magnitude is similar during the first and subsequent encounters - No memory stored
5.1.1 First line
5.1.1.1 Saliva
5.1.1.2 Mucus
5.1.1.3 Tears
5.1.1.4 Stomach acid
5.1.1.5 Skin
5.1.2 Second line

Annotations:

  • Physiological barriers
5.1.2.1 Fever

Annotations:

  • Initiated by pyrogens; Change the hypothalamus
5.1.2.2 Inflammation

Annotations:

  • 1. Redness 2. Heat 3. Pain 4. Oedema
  • Stages: 1. Tissue injury 2. Dilation and increased leakiness of local blood vessels 3. Phagocytes- phagocytosis
5.1.2.3 Phagocytosis

Annotations:

  • 1. Attachment 2. Ingestion 3. Killing 4. Degradation
5.1.2.4 Antimicrobial proteins

Annotations:

  • 1. Interferons Iron-binding proteins 3. Antimicrobial peptides
5.2 Adaptive immune response
5.2.1 Third line
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