Paul Ehrlich

Description

Edexcel iGCSE
Niamh MacElvogue
Mind Map by Niamh MacElvogue, updated more than 1 year ago
Niamh MacElvogue
Created by Niamh MacElvogue almost 10 years ago
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Resource summary

Paul Ehrlich
  1. Ehrlich
    1. Magic Bullet
      1. Had knowledge of germs and so the time was ripe
        1. Wanted to make his own chemical antibody
          1. Working on diphtheria and became interested in antibodies
            1. Ward off germs without damaging body
            2. German chemistry industry rapidly advancing so Ehrlich had a team that he made concentrate on discovering chemical cures for disease
              1. 1899 - began to test synthetic dyes with limited success
                1. Found dyes that would attack malaria and sleeping sickness
                2. Salvarson 606
                  1. Discovered in 1909 by Japanese bacteriologist, Hata, who was testing discarded compounds
                    1. Koch's influence
                    2. Discovered that it killed the syphilis germ
                      1. Tested multiple times
                        1. There were concerns about this work however
                          1. Doctors found it difficult to inject
                            1. It was painful for the patient
                              1. Believed it would cause increase in promiscuity
                              2. Impacts
                                1. Short term
                                  1. Ehrlich was able to find dyes that combatted sleeping sickness and malaria
                                    1. 606's impact on humans was limited as it wasn't accepted within the medical community
                                    2. Long term
                                      1. Over the next 20 years many more magic bullets were discovered including for pneumonia and meningitis
                                        1. Limitations including that they didn't work for everything
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