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Flashcards

Lecture 22 Limbic System

Mia Li 534 Neuroanatomy Inglês 53 flashcards

Flashcards do conjunto (53)

  1. 1Key functions of limbic system:1. olfaction
    2. emotions and drives
    3. homeostasis
    4. memory
  2. 2T/F: All cortex of limbic system are neocortex.F.
    Some are allocortex, some are archecortex
  3. 3Septal nuclei is excited by the transmitters.cholinergic
  4. 4The ventral tegmental area is regulated by the _______ transmitters.dompaminergic
  5. 5The locus ceruleus is regulated by the _______ transmitters.noradrenergic
  6. 6The raphe nuclei are regulated by the _________ transmitters.serotonergic
  7. 7The medial cortical region of limbic system is called the ________.Association cortex
  8. 8T/F: Most association fibers of limbic system run in one direction.F. Usually both directions.
  9. 9Name the structure that serves the following function: 1. smell 2. emotion and drives 3. establishing new memories 4. homeostasis1. smell: olfactory cortex
    2. emotion and drives: amygdala
    3. establishing new memories: hippocampal formation
    4. homeostasis: hypothalamus
  10. 10The limbic system is a collection of cortical gyri buried within the __________.anteromedial telencephalon
  11. 11Key gyri in limbic system:1. cingulate
    2. orbital frontal
    3. rectus
    4. parahippocampal
  12. 12Hyppocampal formation are located (superficial/deep) to the parahippocampal gyri.Deep
  13. 13Anterior to the hippocampal formation is the _________.Amygdala
  14. 14Structure responsible for: 1. conscious detection of smell 2. ordor discrimination1. primary olfactory cortex
    2. orbitofrontal olfactory area
  15. 15the _________ of the parahippocampal gyrus is an important target for the emotional and memory aspect of smell.entorhinal cortex
  16. 16The ________ forms explicit memory.hippocampal formation
  17. 17What are considered as 'explicit memory'?1. conscious cognitive
    2. verbal-based learning processes
  18. 18Location of hippocampal formationdeep to entorhinal cortex
  19. 19Three parts of the hippocampal formation1. dentate gyrus
    2. hippocampus
    3. subiculum
  20. 20T/F: All hippocampal formation are neocortexF.
    Archicortex.
  21. 21Which three layers of cells are in the hippocampal formation?1. molecular layer
    2. pyramidal or granular layer
    3. polymorphic layer
  22. 22The _______ and _______ folds twice.dentate gyrus
    hippocampus
  23. 23The hippocampus forms the ___ of lateral ventricle in the _____ horn.floor (medial wall)
    inferior horn
  24. 24The parahippocampal gyrus ends up on the _____ surface of the medial temporal cortex, around the _______.inferior
    around midbrain
  25. 25Uncus is _______ with mammilary bodies.parallel
  26. 26Many neocortical areas project to the entorhinal cortex, which projects to the _______ gyrus via _______.dentate gyrus
    via the perforant pathway
  27. 27The perforant pathway (or indirect perforant pathway) is important for _________long term synaptic plasticity [long-term potentiation (LTP)]
  28. 283 layers of dentate gyrus from outer to inner1. molecular (outer)
    2. granular (middle)
    3. polymorphic (inner fiber tracts)
  29. 29The perforant pathway from entorhinal input synapse with the ____ cells in the dentate gyrusgranule cells
  30. 30Granule cell axons ( _______ fibers) from dentate gyrus project to the _____ and synapse on _____ pyramidal cells.Granule cell axons [dentate fibers] from dentate gyrus project to the [hippocampus] and synapse on [CA3] pyramidal cells.
  31. 31CA3 axons are called theSchaffer collateral fibers
  32. 32CA3 axons project to _____ neurons.CA1
  33. 33T/F: CA3---CA1 pathway is also long-term potentiation pathway.T.
  34. 34Entorhinal cortex also have direct pathway to _____ and _____ pyramidal cells in the hippocampus. This pathway is called _______.CA1 and CA3
    alvear pathway (direct perforant pathway)
  35. 35The direct perforant pathway leads back to _____ and ______.The subiculum
    and
    entorhinal cortex
  36. 36Feedback loops run from ____ to _____ and then to _______.subiculum --- entorhinal --- association cortex
  37. 37The hippocampus and subiculum also form output paths to limbic system, thalamus, and hypothalamus via ________The fornix
  38. 38Fornix is a white matter tract formed by the axons from _______ and ______ which are directed into the _____.Pyramidal CA1 and CA3
    directed to the fimbria
  39. 39Fibers crossing between hemispheres are called ________. It is continuous with the (anterior/posterior) fornix.hippocampal commisure
    continuous with anterior fornix
  40. 40Non-decussating fornix fibers either 1) bend and descend behind the _____ and end up in the __________. 2) bend and direct anterior to the anterior commissure and terminate in the _________, which is related to our ______ system.1) Behind the anterior commisure
    end up in the mammillary bodies
    2) septal nuclei, reward system
  41. 41Fornix fibers to mammillary bodies -->anterior thalamus --> anterior limb of internal capsule (thalamocortical fibers) --> cingulate gyrus
    This is the second feedback loop to entorhinal cortex
  42. 42T/F: the fornix pathway is bi-directional.T.
  43. 43Outline the Papez circuitparahippocampal entorhinal cortex --> dentate gyrus --> subiculum + hippocampus (pyramidal CA3 to CA1) --> fimbria --> fornix --> mammillary bodies --> anterior thalamus --> internal capsule --> cingulate gyrus --> back to parahippocampal gyrus
  44. 44___________ has a dominant role in emotional aspect of olfaction.Amygdala
  45. 45What happens to the patient if amygdala has lesion?placid, non-aggressive behavior
  46. 46S/S of hyperactive amygdalarage, fear, panic
  47. 47Connections the amygdala has1. limbic cortex
    2. septal nuclei
    3. hypothalamus
    4. brainstem autonomic pathways
  48. 48What are the 3 primary pathways of the amygdala?1. stria terminalis
    2. ventral amygdalofugal
    3. medial forebrain bundle
  49. 49position of stria terminalismedial along caudate
    similar path as fornix
    form amygdala to ventromedial hypothalamus and septal nuclei
  50. 50What does the stria terminalis carry?olfactory input to motivate/inhibit appetite
  51. 51The ventral amygdalofugal pathway projects to ______, _____ and _____ to support emotion, drive, and cognitive functions, and to ______ to impact homeostasis and arousal.septal, basal forebrain, and ventral striatum
    also to hypothalamus
  52. 52The median forebrain bundle carries ________, _____ and ______ fibers to nuclei under ________ control.septal, hypothalamic and brainstem fibers
    to
    autonomic nuclei (vagus, solitary, periaqueductal gray, reticular)
  53. 53unfinishedstart from major neurotransmitter systems

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534 Neuroanatomy FlashCards sobre Lecture 22 Limbic System, criado por Mia Li em 03-12-2017.
Criado por
Mia Li
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