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Pharmacology Vet 202 Chapter Nine Study Guide
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Perguntas do quiz (25)
1The drug of choice for managing seizures long term is an oral barbiturate that has the benefit of being relatively inexpensive while having an extensive half-life. What is this drug?
- ADiazepam
- BPhenobarbital
- CXylazine
- DPotassium bromide
- EPentobarbital
2Over time, barbiturate use results in upregulation of the enzymes responsible for the drug’s breakdown. This phenomenon is known as enzyme __________________.
- Atolerance
- Banabolism
- Cinduction
- Dinactivation
- Emodulation
3Diazepam is a benzodiazepine tranquilizer that, in contrast to phenobarbital which is used as a long-term anti-seizure medication, is instead used as an emergency IV drug for use during an active convulsion. All of the following are characteristics of diazepam except one. Which choice is incorrect?
- AThe mode of action is stimulation of GABA
- BOral dosing is severely limited by an extensive first-pass effect
- CTends to cause withdrawal signs after abruptly ceasing use
- DGood choice for a dog with a history of aggression that is controlled with obedience training
4Which of the following is a property of potassium bromide?
- AHalf-life exceeds 3 weeks
- BDrug of choice for cats with seizures
- COften used as the sole therapy for seizures
- DAntagonizes the effect of phenobarbital if given concurrently
5There are several mechanisms of action for behavior-modifying drugs used in veterinary medicine. Which of the following is not considered one of these mechanisms?
- AModifying neurotransmitter release
- BImitating a neurotransmitter in an agonistic or antagonistic manner
- CModifying neurotransmitter duration by altering chemical breakdown capability
- DStimulate euphoria by binding to the µ opioid receptor
6Which neurotransmitter does acepromazine antagonize to decrease anxiety in both humans and veterinary patients?
- ASeratonin
- BDopamine
- CGlycine
- DGABA
7Which of the following classes of antidepressant medications function by modifying the activity of enzymes that are responsible for the biotransformation of neurotransmitters?
- ATricyclic antidepressants (TCAs)
- BMonoamine oxidase inhibitors (MAOIs)
- CSelective Serotonin Reuptake Inhibitors (SSRIs)
- DAll of the above
8What is the general role of the neurotransmitter serotonin?
- AMood determinant
- BStarting material for catecholamine production
- CCentral nervous system inhibition
- DIncrease parasympathetic nervous system tone
9What is primidone’s primary mechanism of activity?
- ADirectly increases activity of the inhibitory neurotransmitter glycine
- BDirectly decreases the activity of the excitatory neurotransmitter norepinephrine
- CIs metabolized to phenobarbital, so functions to stimulate GABA
- DAgonism of 2-adrenergic receptors
10An uncommonly used unit of measurement that is often used in conjunction with barbiturates is the grain. What is the size in milligrams of a 2-grain phenobarbital tablet?
- A2 mg
- B20 mg
- C120 mg
- D200 mg
11Seizures generally originate from the brain but seizure activity can also arise from other causes. Veterinary technicians should always consider these other sources except:
- Ahypoxia.
- Bhypoglycemia.
- Chypocalcemia.
- Dhypothermia.
12________________ is the term used to describe seizure activity that is prolonged and can result in positive feedback where muscle activity increases temperature and increase seizure activity.
- AIdiopathic
- BStatus epilepticus
- CProdromal phase
- DPostictal phase
13Phenobarbital used to control seizures has a well-established therapeutic range for dogs but dosages vary widely based upon:
- Aweight of the animal.
- Bhow the individual metabolizes the drug.
- Cfrequency of seizures.
- Danimals age.
14Side effects of using phenobarbital to control seizure activity in dogs include
- Aataxia.
- Bpolyuria.
- Cpolyphagia.
- DAll of the above
15Phenobarbital induced hepatotoxicity:
- Ais idiosyncratic in dogs.
- Bhappens more often in cats.
- Cis a common occurrence.
- Dcauses kidney failure.
16On an animal that is not responding particularly well to phenobarbital or the phenobarbital/bromide combination for long-term seizure control, all of the following drugs might be tried except:
- AClomicalm.
- Blevetricetam.
- Cgabapentin.
- Dzonisamide.
17Drugs that “lyse” anxiety or decrease fear responses are called:
- Aantipsychotic drugs.
- Banxiolytic drugs.
- Cantidepressant drugs.
- Dmajor tranquilizers.
18Three classes of antidepressant drugs used in human beings have also found use in veterinary medicine include all except:
- Amonoamine oxidase inhibitors (MAOI)
- Btricyclic antidepressants (TCA’s)
- Cselective serotonin reuptake inhibitors (SSRI’s)
- Dgamma () aminobutyric acid (GABA)
19Clomipramine’s FDA–approved indication is for treatment of obsessive-compulsive disorders in dogs. A more common use of clomipramine in veterinary medicine is for:
- Atreatment of separation anxiety.
- Btreatment of depression.
- Ctreatment of seizures.
- Dtreatment of epilepsy.
20Plasma phenobarbital concentrations achieved with any given dose vary considerably from patient to patient. Therefore, the only way to ensure a dosage regimen is adequate is to
- Amonitor the animal’s behavior.
- Bcheck blood levels of phenobarbital.
- Ccheck frequent blood chemistry panels.
- Dmonitor the animal’s urine output.
21When considering neurotransmitter-modifying drugs for behavior therapy, which of the following is true?
- AUse of these drugs provides an immediate response
- BOnce an effective dose is determined, no further adjustments are needed
- CEvery animal responds differently to these drugs
- DAllows for optimal behavior modification without requiring training
22Potassium bromide is used as an adjunct drug for treating seizures when standard doses of barbiturates prove ineffective alone. Considering the long 3-week half-life of potassium bromide, how would you determine the length of time it takes to reach a steady state when using this drug daily?
- A10.5 days
- B21 days
- C21 weeks
- D105 days
- E201 Days
23Which of the following is not a side effect of barbiturate use?
- APolyphagia
- BPolydactyly
- CPolydipsia
- DPolyuria
24What is the portion of the brain that controls animal emotion and is thus targeted for alteration by behavior-modifying drugs?
- ACerebrum
- BCerebellum
- CLimbic region
- DPituitary gland
- EPineal gland
25In addition to treating behavioral problems, selegiline is also used to treat this condition in dogs.
- ACushing’s disease
- BParkinson’s disease
- CPituitary dwarfism
- DHypoadrenocorticism
Informações
- Descrição
- Veterinary Medicine Quiz sobre Pharmacology Vet 202 Chapter Nine Study Guide, criado por Kelly Kinsinger em 30-10-2018.
- Autor
- Kelly Kinsinger
- Idioma
- English
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