Quiz
PHSI3011 10-2 Adipose in Metabolism
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Questions in this quiz (27)
1Of the 5 cell types of adipose tissue, which are counted as the “stromal vascular fraction”?
- AAdipocytes
- BFibroblasts
- CPreadipocytes
- DVascular endothelial cells
- EImmune cells (e.g. macrophages)
2What proportion of the volume of adipose tissues is taken up by Adipocytes (as opposed to Fibroblasts, Preadipocytes, Vascular endothelial cells, Immune cells)?
- A20%
- B40%
- C60%
- D80%
3What is the effect of Insulin on each of the following things within Adipose tissue?
Glucose uptake: [blank_start]__________[blank_end]
Fatty Acid synthesis: [blank_start]__________[blank_end]
Fatty Acid storage: [blank_start]__________[blank_end]
Protein synthesis: [blank_start]__________[blank_end]
Fatty Acid release: [blank_start]__________[blank_end]- AStimulate
- BInhibit
- CStimulate
- DInhibit
- EStimulate
- FInhibit
- GStimulate
- HInhibit
- IStimulate
- JInhibit
4Adipocytes make triglycerides from which of the following:
- AGlucose
- BFatty Acids
- CCholesterol
5Adipocytes release adipokines like Leptin. Leptin is an example of which of the following:
- ALipids
- BHormones
- CPeptides
- DCytokines
6Adipokines include which of the following:
- ALipids
- BHormones
- CPeptides
- DCytokines
7Adipokines have been shows to influence which of the following:
- AMetabolism
- BFood intake
- CEnergy expenditure
- DInflammation
8True or false: Adipokines are secreted from adipocytes, but can also be secreted from other sites.
- ATrue
- BFalse
9Which gene is missing in the obese “OB” mouse?
- ALeptin
- BAdiponectin
- CGLUT4
10Leptin is released from the adipose tissue, then communicates with the [blank_start]__________[blank_end] to [blank_start]__________[blank_end]/[blank_start]__________[blank_end].
- AHypothalamus
- BHippocampus
- CSUPPRESS energy intake
- DINCREASE energy intake
- ESUPPRESS energy expenditure
- FINCREASE energy expenditure
11True or false: Most obese people are Leptin-deficient.
- ATrue
- BFalse
12Define Lipodystrophy:
- ALACK of fat (in adipose tissue)
- BEXCESS of fat (in adipose tissue)
- CDISRUPTION of function of fat (in adipose tissue)
- DEXCESSIVE function of fat (in adipose tissue)
13Leptin is a key hormone released from adipose tissue and is involved in [blank_start]__________[blank_end] metabolism in the WHOLE BODY.
- AGlucose
- BLipid
- CNeither
- DBoth
14True or false: Leptin therapy is a promising mode of treatment for most obese patients.
- ATrue
- BFalse
15True or false: Leptin therapy is a promising mode of treatment for patients with Type 1 Diabetes.
- ATrue
- BFalse
16True or false: Leptin therapy is a promising mode of treatment for patients with Type 2 Diabetes.
- ATrue
- BFalse
17The adipokine Adiponectin is one of the most highly secreted proteins in our blood. Its secretion is generally [blank_start]__________[blank_end] in obesity.
- AReduced
- BIncreased
- CUnaffected
18[blank_start]__________[blank_end] acts to stimulate AMP-kinase to increase β-oxidation [and] increase glucose uptake into the cell.
- AAdiponectin
- BLeptin
- CBoth of the above
- DNeither of the above
19True or false: In addition to being stimulated by some adipokines, AMP-kinase is also regulated by exercise, to stimulate energy expenditure within a cell.
- ATrue
- BFalse
20Hypertrophy vs Hyperplasia (with a view on adipocytes)
Hypertrophy = increase in [blank_start]__________[blank_end];
Hyperplasia = increase in [blank_start]__________[blank_end].- ASize
- BNumber
21True or false: Ectopic Lipid Accumulation is the “spill over” when adipocytes reach saturation and lipids start getting into other tissues (e.g. muscle, liver) where it causes metabolic dysfunction.
- ATrue
- BFalse
22True or false: Lipodystrophy is the “spill over” when adipocytes reach saturation and lipids start getting into other tissues (e.g. muscle, liver) where it causes metabolic dysfunction.
- ATrue
- BFalse
23Which of the two distributions are more strongly associated with metabolic disease?
“Android” distribution – more around the upper body;
“Gynoid” distribution – more around the lower body.- AGynoid
- BAndroid
24True or false: BMI = Body Mass Index; WHR = Waist-Hip Ratio
- ATrue
- BFalse
25Someone with a higher upper-body fat distribution will need to __________ in order to maintain homeostasis.
- ASecrete MORE insulin
- BSecrete LESS insulin
- CAbsorb MORE insulin
- DAbsorb LESS insulin
26True or false: Chronic inflammation often correlates with obesity because there’s increased migration of macrophages into the ADIPOSE tissue.
- ATrue
- BFalse
27Which of the following are associated with [adipose] hypertrophy and [adipose] hyperplasia?
- AHypoxia
- BFibrosis
- CInflammation
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- PHSI3011 10-2 Adipose in Metabolism
- Author
- Michael Jardine
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- English
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