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Antibacterial Drugs (Antibiotics)- Pharmacology- 4th Year- PMU

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Antibacterial Drugs (Antibiotics)
Med Student
Quiz by Med Student , updated more than 1 year ago
Med Student
Created by Med Student over 5 years ago
133
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Resource summary

Question 1

Question
Bactericidal antibacterial drugs:
Answer
  • inhibit the growth of microorganisms
  • inhibit the multiplication of microorganisms
  • kill the microorganisms
  • block the enzyme penicillinase

Question 2

Question
Antimicrobials with bactericidal activity are:
Answer
  • beta-lactam antibiotics
  • amphenicols and lincosamides
  • aminoglycosides
  • quinolones

Question 3

Question
Bacteriostatic action means:
Answer
  • inhibition of the growth of microorganisms
  • inhibition of the multiplication of microorganisms
  • destruction of microorganisms
  • inhibition of the enzyme penicillinase

Question 4

Question
Bacteriostatic antimicrobials are:
Answer
  • amphenicols
  • aminoglycosides
  • tetracyclines and macroiides
  • lincosamides

Question 5

Question
Narrow spectrum antimicrobial drugs are active against:
Answer
  • Gram (+) cocci
  • Gram (+) bacteria
  • Fungi and viruses
  • Parasites

Question 6

Question
Antimicrobials with a narrow spectrum of activity are:
Answer
  • classic penicillins
  • lincosamides
  • aminoglycosides
  • classic macrolides

Question 7

Question
Antimicrobials with broad spectrum of activity are:
Answer
  • cephalosporins
  • aminopenicilins
  • lincosamides
  • rifamycins

Question 8

Question
Antimicrobials that inhibit bacterial cell wall synthesis are:
Answer
  • penicillins
  • cephalosporins
  • monobactams
  • tetracyclines

Question 9

Question
Antimicrobial that inhibit protein synthesis in microorganisms are:
Answer
  • tetracyclines
  • macrolldes
  • quinolones
  • carbapenems

Question 10

Question
Antibiotics that inhibit DNA synthesis in microorganisms are
Answer
  • cephalosporins
  • quinolones
  • macrolides
  • rifampicin

Question 11

Question
Antibiotics that must be avoided during pregnancy are:
Answer
  • tetracyclines
  • penicillins
  • cephalosporins
  • rifampicin

Question 12

Question
Antimicrobial agents with urine excretion are:
Answer
  • penicillins
  • cephalosporins
  • aminoglycosides
  • quinolones

Question 13

Question
Antimicrobial agents with bile excretion are:
Answer
  • tetracyclines
  • aminoglycosides
  • macrolides
  • sulfonamides

Question 14

Question
Optimal combinations of antimicrobial agents are:
Answer
  • bactericidal antibiotics with bactericidal antibiotics
  • tetracyclines with macrolides
  • bactericidal antibiotics with bacteriostatic antibiotics
  • penicillins with B-lactamase inhibitors

Question 15

Question
Tetracyclines
Answer
  • are bactericidal
  • ae bacterostatic
  • accumulate in tissues- in bones and teeth
  • are effective against rickettsiae, mycoplasma, chlamydia

Question 16

Question
Which foods and drugs interact with tetracyclines' gastrointestinal absorption?
Answer
  • Vitamin B1
  • Yogurt or Cheese
  • Fe2+ or Mg2+ containing drugs
  • Aminoglycosides

Question 17

Question
Adverse drug reactions of tetracyclines are:
Answer
  • nephro-and ototoxicity
  • hepatotoxicity
  • yellow-brown discoloration of teeth and frequent tooth decay in children
  • inhibition of bone growth in children

Question 18

Question
Tetracyclines are contraindicated in:
Answer
  • pregnancy
  • children less than 8 years
  • liver failure
  • heart failure

Question 19

Question
Macrolide antibiotics are:
Answer
  • Azithromycin (Azatril)
  • Roxithromycin (Rulid)
  • Clarithroomycin (Klacid)
  • Gentamycin

Question 20

Question
Macrolides are:
Answer
  • bactericidal
  • bacteriostatic
  • inhibitors of methylxanthines’ metabolism
  • effective against mycoplasmas, Legionella, Chlamydia

Question 21

Question
Adverse drug reactions of macrolides include:
Answer
  • gastrointestinal disturbances
  • allergy
  • hepatotoxicity
  • nephrotoxicity

Question 22

Question
Macrolides are contraindicated in:
Answer
  • Pregnancy in the first half
  • G-6-PDH deficiency
  • Liver failure
  • Breastfeeding

Question 23

Question
Lincosamides:
Answer
  • are bacteriostatic antibiotics
  • are appropriate for the treatment of staphylococcal osteomyelitis
  • can be hepato- and haematotoxic
  • accumulate in the bone marrow

Question 24

Question
Lincosamides are contraindicated in:
Answer
  • pregnancy
  • children less than 2 years
  • liver failure
  • heart failure

Question 25

Question
Chloramphenicol:
Answer
  • is a bactericidal antibiotic
  • is effective against Gram (-) microorganisms
  • is a tetracycline derivative
  • inhibits alcohol dehydrogenase enzyme

Question 26

Question
The correct statements for Chloramphenicol are:
Answer
  • It is used as a reserve antibiotic because of many ADRs
  • Causes gastrointestinal disbacteriosis
  • Can be administered orally
  • It Is used for the treatment of tuberculosis

Question 27

Question
Adverse drug reactions of Chloramphenicol are:
Answer
  • damage of teeth enamel
  • "gray baby" syndrome
  • disulfiram- alcohol reaction
  • bone marrow supression (myelotoxicity)

Question 28

Question
Chloramphenicol is contraindicated in:
Answer
  • Pregnancy
  • Children less than 2 years
  • Alcoholism
  • G-6-PDH deficiency

Question 29

Question
Beta-lactam antibiotics are
Answer
  • penicillins
  • cephalosporins
  • monobactams
  • carbapenems

Question 30

Question
Narrow spectrum (classic) penicillins are:
Answer
  • Amoxicillin
  • Benzylpeniciliin (Penicilin G)
  • Phenoxymethylpenicillin (Ospen)
  • Oxacillin

Question 31

Question
Broad spectrum semisynthetic penicillins are:
Answer
  • Amoxicillin (Amopen)
  • Ampicillin
  • Azlocillin
  • Gentamycin

Question 32

Question
Adverse drug reactions of penicillins are:
Answer
  • allergic reactions
  • hepatotoxicity
  • anaphylactic shock
  • disbactenosrs (for orally administered broad-spectrum penicillins)

Question 33

Question
Penicillins and cephalosporins block the synthesis of:
Answer
  • the bacterial cell wall
  • the bacterial membrane
  • proteins
  • nucleic acids

Question 34

Question
Cephalosporins 1st generation are:
Answer
  • More effective against Gram (+) microorganisms
  • Cefalexin and Cefazolin
  • Bacteriostatic
  • Some agents are nephrotoxic

Question 35

Question
Cephalosporins 2nd generation are:
Answer
  • Bactericidal
  • Cefaclor and Cefamandol
  • More effective against Gram (-) organisms: Klebsiella, H. lnfluenzae
  • With high bile concentrations (most of them)

Question 36

Question
Cephalosporins 3rd generation are:
Answer
  • Cefetamet and Ceftriaxon
  • Cefaclor and Cefamandol
  • More effective against Gram (-) microorganisms
  • Used for treatment of life-threatening infections

Question 37

Question
Cephalosporins 4th generation are:
Answer
  • Cefepim and Cefpifom
  • Narrow spectrum antibiotics
  • Effective against Gram (-) microorganisms as 3rd generation and against Gram (+) as 1st generation cephalosporins
  • Used for treatment of life-threatening infections

Question 38

Question
Adverse drug reactions of cephalosporins are:
Answer
  • allergic reactions
  • suppressed vitamin K synthesis
  • hepatotoxicity
  • nephrotoxicity

Question 39

Question
Aminoglycoside antibiotics are:
Answer
  • Gentamaicin
  • Amoxiclav
  • Amikacin
  • Tobramycin

Question 40

Question
The correct statements of aminoglycoside antibiotics are:
Answer
  • they block protein synthesis and are bactericidal
  • they accumulate in soft tissues and bones
  • they are administrated orally for treatment of urinary infections
  • they are effective against Gram (-) microorganisms

Question 41

Question
Adverse drug reactions of aminoglycosides are:
Answer
  • nephrotoxicity
  • ototoxicity
  • myelotoxlcity
  • hepatotoxiclty

Question 42

Question
Aminoglycosides are contraindicated in:
Answer
  • pregnancy
  • children less than 2 years
  • renal failure
  • liver failure
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