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Leucocyte Pathologies

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Haematology and Anatomy (Leukocytes) Quiz on Leucocyte Pathologies, created by gina_evans0312 on 09/01/2014.
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Quiz by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312 over 10 years ago
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Resource summary

Question 1

Question
In Flow Cytometry, cell size is measured as they pass through laser beams
Answer
  • True
  • False

Question 2

Question
Why is this area left?
Image:
Flow_Cytometry (image/png)
Answer
  • Excludes cells with low CD45
  • Excludes small cells
  • Excludes cells too large to pass through

Question 3

Question
In Flow Cytometry, the Ig tested for varies depending on which cell you're measuring
Answer
  • True
  • False

Question 4

Question
For which cell would you use an alkaline reagent?
Answer
  • Eosinophils
  • Basophils
  • Monocytes

Question 5

Question
Normal range of W.B.C's is 4-11 (x10^7/l)
Answer
  • True
  • False

Question 6

Question
What is to be expected in a Settling test from a leukaemia patient?
Answer
  • Thinker plasma layer
  • Thicker buffy coat layer
  • Thicker erythrocyte layer

Question 7

Question
Why is a strong lysing solution added to a W.B.C count?
Answer
  • Remove R.B.C's
  • Remove platelets

Question 8

Question
Like R.B.C's, W.B.C's are counted using current impedence
Answer
  • True
  • False

Question 9

Question
What are the two populations (peaks) shown here?
Image:
W.B.C_Count (image/png)
Answer
  • Lymphocytes
  • Monocytes
  • Nutraphils
  • All others

Question 10

Question
What two things are mapped in D.I.F.F?
Answer
  • Size
  • Shape
  • Granularity
  • Markers

Question 11

Question
What cells are being pointed at on the graph?
Image:
D.I.F.F (image/png)
Answer
  • Netraphils
  • Monocytes
  • Lymphocytes

Question 12

Question
Cellpack & Stromatolyers 3D do what?
Answer
  • Protect W.B.C's
  • Speed R.B.C's lysis

Question 13

Question
List some causes of Neutropenia
Answer
  • Overwhelming bacterial/viral/funal/parasitic infections
  • Anti-cancer drugs
  • Irradiation
  • Aplastic Anaemia

Question 14

Question
Chronic infection/inflammation and increased cytokinase can lead to high...
Answer
  • Monocytes
  • Eosinophils
  • Basophils

Question 15

Question
Basophilia is caused by
Answer
  • Leukaemias
  • Allergic recations

Question 16

Question
Eosinophilia is caused by allergic infections, parasitic infections and drug hypersensitivity
Answer
  • True
  • False

Question 17

Question
Name some causes of Lymhpocytopenia
Answer
  • AIDs
  • Carcinoma
  • Renal failure
  • Vigerous exercise/Smoking

Question 18

Question
Name the three tests done for any Leucocytic disorder
Answer
  • Flow Cytometry
  • Full blood count & DFF
  • NAP test
  • Paul Bunnell Test
  • Morphology

Question 19

Question
Why does Clonality indicate a severe pathology?
Answer
  • A single cell type is proliferating massively
  • Shows a lack of diversity across leucocytes
  • Shows massive infection

Question 20

Question
What markers do you test for when looking for Clonality?
Answer
  • Kappa/lambda markers
  • CD4/CD8
  • Alpha, beta & gamma

Question 21

Question
In AIDS, you perform flow cytometry for Kappa/Lambda markers
Answer
  • True
  • False

Question 22

Question
The Paul Bunnel test is done for...
Answer
  • Viruses
  • Fungi
  • Bacteria

Question 23

Question
Name the cause of Haematological Malignancies
Answer
  • Genetics
  • Drugs
  • Irradiation
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