Quiz
Coagulation and Coagulation Disorders
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Questions in this quiz (36)
1The Extrinsic Pathway operates on the initiating cell
- ATrue
- BFalse
2What is the role of the Extrinsic Pathway?
- ACoagulation initiation
- BFormation of the fibrin plug
- CActivation of Factor V
3The Intrinsic Pathway works on...
- AThe endothelium
- BThe vW factor
- CThe platelet surface
4The Intrinsic pathway is designed to generate thrombin bursts
- ATrue
- BFalse
5Name the three steps of Coagulation
- AInitiation
- BAmplification
- CPropagation
6What begins the Initiation phase?
- AVascular injury initiates trigger factor
- BVascular injury exposes collagen for platelets to bind
- CVascular injury causes blood cells to lyse
7Trigger factor activates VII, which activates smal amounts of
- AIX
- BX
- CXI
8X & XI bind to platelets and produce small amounts of Thrombulin
- ATrue
- BFalse
9Thrombin initiates Amplification
- ATrue
- BFalse
10The platelets act as a surface for the assembly of what factor complexes?
- AIX & VIII
- BPrethrombinase (X & V)
11What happens in Propogation
- AActivated platelets/complexes generate Thrombin Burst
- BActivated platelets/complexes generate Thrombulin Burst
- CActivated platelets/complexes generate Thromblin Burst
12What two things are required for Fibrin Clot formation?
- AFibrinogen --> Fibrin
- BF IIa
- CF III
- DF V
13Thrombin production is the crucial step in haemostasis
- ATrue
- BFalse
14The first step in Coagulation Disorder diagnosis is a family & drug history
- ATrue
- BFalse
15Name the two main clinical presentation of coagulation disorders
- ABleeding in deep tissues
- BBleeding in joints
- CFlushed skin
- DEasy cutting of skin
16Prethrombin Time is anassessment of the _ Pathway
- AExtrinsic
- BInstrinsic
17Prethrombin time is expressed as an international, normalised ratio
- ATrue
- BFalse
18Activated Partial Thromboplastin Time is an indicator of...
- AIntrinsic pathway
- BExtrinsic pathway
19Which of the following are not Coagulation Disorder investigations?
- AFibrinogen Assay
- BFXIII Screen
- CThrombin Clotting Time
- DFibin Clotting Time
20How do you evaluate increased prethrombin time?
- AMix with normal platelets (50:50)
- BRemove half the platelets from a sample
- CThen a Factor VII assay
21How do you evaluate Activated Partial Thromboplastin Time (APPT)?
- AMix with normal plasma
- BThen do a Factor VIII, IX, XI assay
- CThen a FXII assay
22Lack o Factor X causes no symptoms
- ATrue
- BFalse
23Factor I assay is used if bot PT and APTT is elevated
- ATrue
- BFalse
24If both PT and APTT is normal, what is tested for?
- AFactor XIII
- BTCT
- CFactor X
25Aquired Coagulation Deficiencies are caused by a lack of what?
- AVit A
- BVit B
- CVic D
- DVit K
26What can cause Aquired Vit K deficiency?
- ADIC
- BMassive Transfusion Effect
- CMalabsorption
27Vit-K deficiency can be drug induced i.e. in the case of liver disease
- ATrue
- BFalse
28Haemophilia A is caused by what?
- AFactor VIII deficiency
- BFactor VI deficiency
- CFactor V deficiency
29Haemophilia A is sex linked
- ATrue
- BFalse
30Haemophilia B is a Factor IX deficiency
- ATrue
- BFalse
31The mutations for Haemophilia A & B are found on which chromosome?
- AX
- BY
32How do you identify Haemophilia B?
- AInc PT
- BInc APTT
- CFactor IX assay
33Von Willebrands disease is caused by a lack of factor
- AVIII
- BVII
- CVI
34vW disease is detected by
- AFVIII Assay
- BvWF assay
35Since many things can effect the levels of vWF, testing is difficult
- ATrue
- BFalse
36vW disease can be qualitative or quantitative
- ATrue
- BFalse
Information
- Description
- Haematology and Anatomy (Coagulation) Quiz on Coagulation and Coagulation Disorders, created by gina_evans0312 on 09/01/2014.
- Author
- gina_evans0312
- Language
- English
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- 553
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