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Pharmacology Vet202 Chapter 8 Study Guide

Kelly Kinsinger 25 Fragen

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  1. 1The first step of the pain perception pathway involves the sensation of a noxious stimulus and the subsequent transmission of the painful signal. This process is known as
    1. Adepolarization transmission.
    2. Bpain perception.
    3. Cstimulus transduction.
    4. Dwind-up.
  2. 2When a painful injury occurs, it’s not just those tissues that are directly damaged that stimulate pain receptors. Over time nearby cells become excessively sensitized and therefore are easily stimulated to detect pain. The resulting throbbing pain found areas near an injury are because of tissue ______________.
    1. Anecrosis
    2. Bhyperalgesia
    3. Chypoesthesia
    4. Dresistance
  3. 3Which opioid receptor is primarily responsible for the profound analgesia that is characteristic of these narcotics?
    1. AmuBild zu Antwort A
    2. BkappaBild zu Antwort B
    3. CdeltaBild zu Antwort C
    4. DalphaBild zu Antwort D
  4. 4Which of the opioids is considered the standard to which all other opioids are compared in terms of analgesic effects, which are resulting from its primary activity at the µ (mu) receptor?
    1. AHydromorphone
    2. BHydrocodone
    3. CFentanyl
    4. DMorphine
  5. 5Of the following, which is a correct when considering topical or transdermal fentanyl delivery to veterinary patients.
    1. AFentanyl doesn’t readily penetrate human skin, so gloves aren’t required
    2. BDisposal of fentanyl patch should be in a conventional household trash bin
    3. CPets are safe to handle by family members 48 hours post-administration of topical fentanyl
    4. DInadvertent exposure to fentanyl, either orally or topically, is considered a medical emergency
  6. 6Buprenorphine is an opioid analgesic that is considered to have both agonist and antagonist opioid receptor effects, which allows for the benefit of providing a long duration of effect with fewer adverse effects compared to other drugs in this class. Buprenorphine exhibits agonistic activity at the ___________ receptor, and antagonistic activity at the _____________ receptor.
    1. A (kappa),  (mu)
    2. B (mu),  (kappa)
    3. C (kappa),  (delta)
    4. DBoth  (kappa) and (theta)
  7. 7Several opioids such as butorphanol and buprenorphine exhibit a limited effect of analgesia regardless of the dose that is administered. This is a phenomenon called the ____________ effect.
    1. Atolerance
    2. Bduration
    3. Cceiling
    4. Dplateau
  8. 8Acepromazine is a commonly used phenylthiazine tranquilizer used often as a premedication in preparation for general anesthesia induction. Which of the following adverse effects has been discounted recently in regards to veterinary use?
    1. AReduce the seizure threshold in dogs
    2. BPotential for causing penile prolapse in stallions
    3. CUse can confound results of allergic skin testing
    4. DCan cause dangerous hypotension in animals experiencing hemorrhage
  9. 9Sedative drugs that are members of the alpha-2 agonists include xylazine and dexmedetomidine. What is the mechanism of action of these drugs at their specific adrenergic receptor?
    1. AIncrease peripheral vasoconstriction
    2. BReduce norepinephrine in the synapse
    3. CImprove cardiac output by increasing heart stroke volume and heart rate
    4. DIncrease bronchial dilation
  10. 10All of the alpha-2 agonists exhibit both alpha-1 and alpha-2 activity to some degree. Rank the alpha-2 agonists in order form those with the highest ratio of activity of alpha-2:alpha-1, to that with the lowest.
    1. ADetomidine>dexmedetomidine>xylazine
    2. BXylazine>dexmedetomidine>detomidine
    3. CDexmedetomidine>xylazine>detomidine
    4. DDexmedetomidine>detomidine>xylazine

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Veterinary Medicine Quiz am Pharmacology Vet202 Chapter 8 Study Guide, erstellt von Kelly Kinsinger am 22/10/2018.
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