Karteikarten
proteins
Karten in diesem Stapel (27)
- 1fibrous protein shaperegular, simple, linear structures that are arranged in long strands or sheets
- 2globular protein shaperoughly spherical in shape
- 3membrane proteinin association with various membranes of cells (embedded in hydrophobic lipid membranes)
- 4primary proteinssequence of amino acids in the polypeptide
- 5secondary proteininitial folding of the polypeptide
- 6tertiarydimensional arrangement of all atoms in a polypeptide
- 7quaternary proteinarrangement of 2 of more polypeptide chains
- 8how is protein read? (from what terminus to the other terminus?) also give how in abbreviations and symbols it would be readn terminus to c terminus
can be written like Ser-Gly-Tyr-Ala-Leu
or SGYAL - 9what are the types of secondary structure proteins?alpha helix, beta conformation, beta turn, and random coils
- 10define an alpha helix structurea backbone wound around an imaginary longitudinal axis, R groups protrude out from the backbone
- 11what kind of bond does the alpha helix maximize?hydrogen bonds
- 12which way to alpha helixes usually turn first? (think right handed and left handed)turn towards the right first (right handed)
- 13interactions between what can stabilize or destabilize an alpha helix? what about he formation of ____ that stabilizes? what effect also stabilizes? what destabilizes?R chains spaced 3-4 residues apart
a formation of ion pairs and the hydrophobic effect stabilize
charge, size, and shape of R chains can destabilize - 14what two amino acids occur infrequently in alpha helixes and why?proline & glycine
proline -> introduces destabilizing kink in helix (because the nitrogen atom is part of a rigid ring, the rotation around the N-C bond isn't possible)
glycine -> high conformational fledibility - 15describe the structure of a beta conformation. include beta strands and sheet structure as wellbackbone extends into a zigzag
beta strand -> single protein segment
beta sheet -> several strands in beta conformation side by side - 16what two types of beta sheet conformations are there? describe themantiparallel -> oposite orienttion
ex: sheet one: ---->
sheet two: < -----
sheet three: ------->
parallel -> same orientation
ex: sheet one: ----->
sheet two: -------> - 17what are b turns? how many residues do they invole? what amino acids are commonly in b turns? what type of bond forms between the residues?connect ends of two adjacent segments of an antiparallel b sheet
involve 4 residues
glycine (residue 2) and proline (residue 3) are often involved
hydrogen bonds form between the 1st residue and the 4th residue - 18what kind of bonds and interactions hold interacting segments in positon for ter tertiary structure proteins?weak interactions and covalent bonds
- 19intrinsically disordered proteinslacking stable tertiary structures
- 20what do fibrous proteins do?give strength and flexibility to structures
- 21what are some types of fibrous proteins?alpha keratin, collagne, & silk fibroin
- 22what do globular proteins contian?enzymes, transports proteins, motor proteins, regulatory proteins, & immunoglobulins
- 23folding motifsrecognizable folding patterns in globular proteins involving 2+ elements of secondar ystructures adn their connections
example: beta-alpha-beta loop or a beta barrel - 24alpha beta barrelbeta-alpha-beta loops arranged where the beta strands form a barrel
- 25what do intrinsically disordered proteins lack?definable structure & a hydrophobic core (usually)
- 26protomerrepeating structural unit of a multimer (multi-subunit protein)
- 27list these functional groups from first priority to last priority: CHO, NH2, CH3, SH, CHO, OH, COOH, CH2,OHSH > OH > NH2 > COOH > CHO > CH2OH > CH3
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- college biochemistry (exam 2 : proteins) Karteikarten am proteins, erstellt von scout bolick am 24/09/2024.
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- scout bolick
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