Channels

Channels

1. Leak of Non-gated channels

   • Channels that open and close spontaneously
     • Ionotropic Receptors

2. Voltage-gated channels

   • Channels that open in response to a change in membrane potential

3. Ligand-gated channels

   • Channels that open in response to chemical binding

4. Sodium Channels (Na+)

   • Excitatorory

5. Chloride channels (Cl-)

   • Inhibitory

6. Mechanically gated ion channels

   • Somatosensory receptor
     • relays extracellular stimulus
       • intracellular signal transduction
   • Mechanoreceptors
     • somatosensory receptor
       • relays extracellular stimulus
         • to intracellular transduction
           • through mechanically gated ion channels