Pathology - Heart Conditions Continued

1. Elevated filling (diastolic) pressures
2. dyspnea
3. insufficient cardiac output

1. Overloaded LS Heart dysfunction (most common)
2. chronic RV pressure overload

1. elevated R atrial and systemic venous pressures
2. Renal dysfunction

1. Increased demands on heart via hypertension --> pressure overload & ventricular hypertrophy

1. Most common, result of systemic Hypertension

Anmerkungen:

• stems from pressure overload of right ventricle.  charcterized by right ventricular hypertrophy and dilation.

1. Caused by pulmonary hypertension
   1. Most commonly occurs as complication of LS HD
2. Morphology
   1. Marked dilation of right V w/out hypertrophy (Acute)
   2. thickening of R ventricular wall (chronic)

1. Thickened ventricular wall
   1. Impaired diastolic filling
2. Microscopic
   1. increased in transverse diameter of myocytes (early stages)
   2. cellular and nuclear enlargment, along/w interstitial fibrosis (late stages)