Zusammenfassung der Ressource
Medicine Through Time: Sulphonamides and Penicillin
- Gerhard Domagk found a dye which stopped Streptococci
- 1932: Domagk discovered a red dye, Prontosil, Stopped the Streoptococcus
microbe from multiplying in mice - Without being poisonous to them.
- 1935: Domagk's Daughter caught the disease. He gave her a large dose of Prontosil and she Recovered
- The active ingredient was identified as Sulphonamide. Many drugs based on these followed.
- Unfortunately, Sulphonamide drugs were found the Damage the Liver and Kidneys
- Florey and Chain found a way to Purify Penicillin
- Penicillin needed purifying as it was a natural product, so These two developed it.
- At first they didn't have the resources to mass-produce it.
- They knew it was vital for treating wounds recieved by soldiers in WWII. Britain was too busy making bombs, so they went to America
- 1941: America joined the War and Mass production stared in 1944
- 1945: Fleming, Florey and Chain were awarded the Nobel Prize