Quiz
Intro to virology
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Questions in this quiz (31)
1The outer surface of the capsid mediates with host cells.
- ANaked Virus
- BEnveloped Virus
2The glycoproteins anchored in the envelope and pointing out mediate contact with the host cells.
- ANaked Virus
- BEnveloped Virus
3Which type of virus is especially Sensitive to lipid solvents (ex. Chloroform, ether) and also to non-ionic detergents.
- ANaked Viruses
- BEnveloped Viruses
4[blank_start]Naked[blank_end] viruses tend to be more stable to environmental changes than [blank_start]enveloped[blank_end] viruses.
- ANaked
- BEnveloped
- CNaked
- DEnveloped
5[blank_start]Enveloped[blank_end] viruses are usually transmitted via aqueous environment: e.g. various body secretions, blood
- ANaked
- BEnveloped
6[blank_start]Naked[blank_end] viruses may be transmitted by many routes: e.g. secretions/blood, oral-fecal, skin contact
- ANaked
- BEnveloped
7What viral structure is defined as a lipid bilayer derived from host cell membranes during the process of virus maturation.
- AVirion
- BCapsid
- CEnvelope
- DNucleocapsid
8Which viral structure is defined as a protein shell that surrounds and protects the viral genome?
- AVirion
- BCapsomer
- CNucleocapsid
- DEnvelope
- ECell wall
- FCapsid
9[blank_start]Icosahedral[blank_end] structures approximate spheres.
- AIcosahedral
- BHelical
10Icosahedral structures can have which of the following axis/axes of symmetry? (Select all that apply)
- Anone. Icosahedral is not symmetrical.
- Btwo-fold
- Cthree-fold
- Dfour-fold
- Efive-fold
11Helical structures can have which of the following axis/axes of symmetry? (Select all that apply)
- ANone. Helical structures are not symmetrical.
- Btwo-fold
- Cthree-fold
- Dfour-fold
- Efive-fold
12The Corona family of viruses is classified as
- [blank_start]Enveloped[blank_end]
-[blank_start]RNA[blank_end] virus
-with [blank_start]helical[blank_end] symmetry of the capsid. -It has a [blank_start]positive[blank_end], [blank_start]single-stranded[blank_end], [blank_start]non-segmented[blank_end] genome.
-It is virion polymerase [blank_start]negative[blank_end].
-It's genome size is [blank_start]16-21[blank_end] kb.- AEnveloped
- BNaked
- CRNA
- DDNA
- Ehelical
- Ficosahedral
- Gpositive
- Hnegative
- Isingle-stranded
- Jdouble stranded
- Knon-segmented
- L10-18 segment
- M3 Segment
- N8 Segment
- O2 Segment
- P2 copies
- Qnegative
- Rpositive
- S16-21
- T22-27
- U8
- V7.2-8.4
- W10
- X12
- Y3.5-9
- Z12.7
- AA13-16
- AB13.5-21
- AC13.6
- AD16-20
- AE10-14
13The Reo family of viruses is classified as
-[blank_start]Naked[blank_end]
-[blank_start]RNA[blank_end] virus
-with [blank_start]Icosahedral[blank_end] symmetry of the capsid.
-It has a [blank_start]double-stranded[blank_end], [blank_start]10-18 segment[blank_end] genome.
-It is virion polymerase [blank_start]positive.[blank_end]
-It's genome size is [blank_start]22-27[blank_end] total in kb.- ANaked
- BEnveloped
- CRNA
- DDNA
- EIcosahedral
- FHelical
- Gdouble-stranded
- Hsingle-stranded
- I10-18 segment
- Jnon-segmented
- K2 copies
- L3 segment
- M8 segment
- N2 segment
- Opositive.
- Pnegative.
- Q22-27
- R8
- S7.2-8.4
- T10
- U12
- V3.5-9
- W16-21
- X12.7
- Y13-16
- Z16-20
- AA10-14
14The Calici family of viruses is classified as a:
-[blank_start]Naked[blank_end]
-[blank_start]RNA[blank_end] virus
-with [blank_start]Icosahedral[blank_end] symmetry of the capsid.
-It has a [blank_start]positive, single-stranded, non-segmented[blank_end] genome.
-It is virion polymerase [blank_start]negative[blank_end].
-It's genome size is [blank_start]8[blank_end] total in kb.- ANaked
- BEnveloped
- CRNA
- DDNA
- EIcosahedral
- FHelical
- G(+) single-stranded, non-segmented
- Hdouble-stranded, 10-18 segment
- I(+) single-stranded, 2 copies
- J(-) single-stranded, non-segmented
- K(-) single stranded, 3 segment
- L(-) single stranded, 8 segment
- M(-) single-stranded, 2 segment
- Nnegative
- Opositive
- P8
- Q22-27
- R7.2-8.4
- S10
- T12
- U3.5-9
- V16-21
- W12.7
- X13-16
- Y13.5-21
- Z13.6
- AA16-20
- AB10-14
15The Picorna family of viruses is classified as a:
-[blank_start]Naked RNA[blank_end] virus with [blank_start]Icosahedral[blank_end] symmetry of the capsid.
-It has a [blank_start]positive, single-stranded, non-segmented[blank_end] genome.
-It is virion polymerase [blank_start]negative[blank_end].
-It's genome size is [blank_start]7.2-8.4[blank_end] total in kb.- ANaked RNA
- BNaked DNA
- CEnveloped RNA
- DEnveloped DNA
- EIcosahedral
- FHelical
- G(+) single-stranded, non-segmented
- Hdouble-stranded, 10-18 segment
- I(+) single-stranded, 2 copies
- J(-) single-stranded, non-segmented
- K(-) single-stranded, 3 segment
- L(-) single stranded, 8 segment
- M(-) single stranded, 2 segment
- Nnegative
- Opositive
- P7.2-8.4
- Q22-27
- R3.5-9
- S13.5-21
- T8
16The Flavi family of viruses is classified as a(n):
-[blank_start]Enveloped RNA[blank_end] virus with [blank_start]Icosahedral[blank_end] symmetry of the capsid.
-It has a [blank_start](+) ss continuous[blank_end] genome.
-It is virion polymerase [blank_start]negative[blank_end].
-It's genome size is [blank_start]10[blank_end] total in kb.- AEnveloped RNA
- BEnveloped DNA
- CNaked DNA
- DNaked RNA
- EIcosahedral
- FHelical
- G(+) ss continuous
- H(-) ss continuous
- I(-) ss, 3 segment
- J(-) ss, 8 segment
- K(-) ss, 2 segment
- LDS, 10-18 segment
- M(+) ss, 2 copies
- Nnegative
- Opositive
- P10
- Q12
- R8
- S13-16
- T13.5-21
- U13.6
17The Toga family of viruses is classified as a(n):
-Enveloped RNA virus with Icosahedral symmetry of the capsid.
-It has a (-) ss continuous genome.
-It is virion polymerase negative.- ATrue
- BFalse
18Which family of viruses has the following characteristics?
-Enveloped RNA virus with Icosahedral symmetry of the capsid.
-It has a (+) ss 2 copies genome architecture.
-It is virion polymerase positve.- ARetroviruses
- BFlaviviruses
- CTogaviruses
- DCorona viruses
- ERhabdoviruses
19Which of the following family of viruses have a (-) single stranded, non-segmented genome architecture? (Select all that apply)
- AReoviruses
- BFlaviviruses
- CTogaviruses
- DRetroviruses
- ECoronaviruses
- FFiloviruses
- GRhabdoviruses
- HParamyxoviruses
- IArenaviruses
- JBunyaviruses
20Which of the following can the smallest possible genome size?
- ACorona viruses
- BRhabdoviruses
- CArenaviruses
- DFlaviviruses
- EPicornaviruses
- FRetroviruses
21Adenoviruses is a kind of RNA virus
- ATrue
- BFalse
22Herpes virus, Pox viruses, Togaviruses, and Rhabdoviruses are all enveloped viruses
- ATrue
- BFalse
23Which of the following Naked DNA viruses have a linear genome architecture? (Select all that apply)
- AParvoviruses
- BPapovaviruses
- CAdenoviruses
- DPicornaviruses
- EArenaviruses
24Filoviruses do not have virion polymerases.
- ATrue
- BFalse
25The pox virus is a Helical enveloped DNA virus.
- ATrue
- BFalse
26Which of the following does not go with the others?
- ACaliciviruses
- BPicornaviruses
- CFlaviviruses
- DTogaviruses
- ERetroviruses
- FCoronaviruses
27The virus life cycle:
1. [blank_start]Attachment[blank_end] - virus [blank_start]binding[blank_end] to cellular receptor(s)
2. [blank_start]Entry[blank_end] - [blank_start]receptor-mediated[blank_end] endocytosis or fusion of viral envelope with cell membrane
3. [blank_start]Uncoating[blank_end] - [blank_start]depends on entry process[blank_end]
4. [blank_start]Replication[blank_end] - [blank_start]depends on type of virus[blank_end]
• [blank_start]mRNA[blank_end] transcription
• [blank_start]protein[blank_end] translation
• [blank_start]nucleic acid[blank_end] replication
5. [blank_start]Assembly[blank_end] - depends on type of virus
6. [blank_start]Release[blank_end] - [blank_start]naked viruses[blank_end] generally release by cell [blank_start]lysis[blank_end]; enveloped viruses release by membrane budding- AAttachment
- Breceptor-mediated
- CmRNA
- Dprotein
- Enucleic acid
- Fnaked viruses
- Gdepends on type of virus
- Hdepends on entry process
- IEntry
- JUncoating
- KRelease
- LAssembly
- MReplication
- Nbinding
- Olysis
28Types of Virus Infection
[blank_start]Acute[blank_end] – infection of a permissive cell: results in virus production, may result in cell death (lytic infection)
[blank_start]Abortive[blank_end] – infection of a non- or semi-permissive cell: block to virus production at some step so infection
aborts
[blank_start]Persistent[blank_end] – long-lasting virus infection. Can be chronic, latent or slow.- AAcute
- BAbortive
- CPersistent
29Persistent infections:
• [blank_start]Chronic[blank_end]-low levels of virus produced over a long time, chronic virus production and reinfection of cells
• [blank_start]Latent[blank_end]- virus goes dormant following primary infection, may reactivate infection at subsequent times
• [blank_start]Slow[blank_end]: virus production increases slowly over time- AChronic
- BLatent
- CSlow
30Productive infection- Sequence of events
1. [blank_start]Virus enters susceptible cells[blank_end]
2. [blank_start]Replication: Transcription / translation[blank_end] of viral genes
3. Viral [blank_start]genome replication occurs[blank_end]
4. [blank_start]Assembly, maturation, and release[blank_end] of virus particles
5. Generally (but not always) [blank_start]results in death[blank_end] of the host cell- AVirus enters susceptible cells
- BReplication: Transcription / translation
- Cgenome replication occurs
- DAssembly, maturation, and release
- Eresults in death
31Latent Infection: Sequence of events
1.Virus [blank_start]enters susceptible cells[blank_end]
2. [blank_start]Transcription / translation of latency[blank_end] associated viral genes Viral genes for lytic replication not expressed
3.[blank_start]Maintenance of the viral genome[blank_end]
4. [blank_start]No progeny virions produced[blank_end]
5. [blank_start]Reactivation of viral gene expression[blank_end] results in lytic gene expression and production of infectious virus- Aenters susceptible cells
- BTranscription / translation of latency
- CMaintenance of the viral genome
- DNo progeny virions produced
- EReactivation of viral gene expression
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