BLOOD

BLOOD

1. Functions

   • Protection
     • by:
       • Antibodies
   • Prevents blood lose
   • Transports
     • Hormones
     • Oxygen
     • CO2
   • Keeps
     • Temperature
     • pH
     • Volume

2. Hematocrit

   • Males
     • 47%
   • Females
     • 42%

3. Eritrocytes

   • 45%
     • Transport Oxygen
   • Have
     • Hemoglobine

4. Buffy Coat

   • has:
     • Leukocytes
     • and:
       • Platelets

5. Characteristics

   • Sticky
   • Opaque Fluid
   • Dense
   • Salty
   • Scarlet color
   • Matallic Taste
   • Viscous

6. Plasma

   • 65%

7. FORMED ELEMENTS

   • Erytrhocytes
     • Small cells
       • 7,5 um
     • Shape
       • Biconcave
     • Anucleate cells
       • Don´t have
         • Organelles
     • Have
       • Hemoglobin
         • Transport Oxygen
       • Spectrin
         • in:
           • Membrane
     • Hemoglobin
       • Globin
         • Desoxyhemoglobin
           • Oxyhemoglobin
             • Without
               • O2
           • With
             • O2
       • Heme Protein
   • Blood Plasma
     • Contain
       • Nutrients
       • Gases
       • Hormones
       • Wastes
       • Proteins
       • Ions

8. WHITHE BLOOD CELLS

   • Platelets
     • Shape
       • Discoid Fragments
     • Cointain
       • Granules
     • 2-4 um
     • 150000- 400000
   • Neutrhopiles
     • Nucleus
       • Multilobuled
     • Cytoplasmatic nucleous
     • 10 - 12 um
     • 3000 - 7000
     • Phagocyte bacterias
   • Granulocytes
     • Eosinophyles
       • Nucleus
         • Billobed
       • Granules
         • Red
       • 10 - 14 um
     • Basophiles
       • Nucleus
         • Billobed
     • Granules
       • 10 - 14 um
   • Agranulocytes
     • Limphocyte
       • nucleus:
         • Spherical
       • 5 - 7 um
       • Attacks:
         • Antibodies
     • Monocytes
       • Nucleus shape:
         • Kidney
         • 14 - 24 um
       • Phagocitocys

9. HEMOSTASIS

   • Mains:
     • Coagulation
       • Process by:
         • Wich blood changes
           • From a:
             • Liquid to gel
     • Platelets
       • Samall colorless
       • Shape
         • Disc
       • Without
         • Nucleous
     • Hemostasis
       • Process by
         • Wich the body
           • Seals a ruptured blood vessels
             • and prevents;
               • Loss of blood
     • Von Willebrand Factor
       • Glycoprotein
         • Circulated in blood plasma
           • Mediates
             • Platelets adhesion
               • to:
                 • Collagen at sites
                   • of
                     • Vascular Injury
   • Steps:
     • 1.- Vascular Spams
       • 2..- Platelet plug formation
         • 3.- Coagulation

10. CLOT RETRACTION AND FIBRINOLYSIS

    • Platelets
      • Induced
        • Clot retraction
      • Have
        • Actin
          • and:
            • Myosine
      • Are stimulated by:
        • Platelet derive growth factor
          • Endothelial cell secrets:
            • Tissue plasminogen activator
              • then
                • Plasmins activity
                  • Destroy the:
                    • clote
    • Blood vessel injury
      • is removed by:
        • Fibrinolysis
          • Without this process
            • Carry of blood is:
              • Blocked

11. TRANSFUSION AND BLOOD REPLACEMENT

    • Transfusing RBC
      • Losing <30%
        • Several shock
        • Transfision
          • 1.- Donor
            • 2.- Blood mixing
              • with:
                • Anticoagulant
              • 3.- Duration:
                • 4° C
                • 35 days
      • RBC Membrane
        • has:
          • Glycoproteins that are:
            • Antigens
              • and:
                • Promote Agglutination
    • Human blood Groups
      • People
        • Differents types of:
          • Blood
        • Transfusion with:
          • Incompatible blood
            • can be:
              • Fatal

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