Classification of the Immune System

Adaptative immune system
1. Humoral immunity
  1. Mediated by B-cells
    1. Matures in the bone marrow
      1. Plasma cells
        Secretes antibodies
      2. Memory B-cells
        Produce plasma cells that directly secrete IgG antibodies in second exposure to antigen
2. Cellular immunity
  1. Mediated by T-cells
    1. Active other immune cells to fully mature
      1. CD8+cytotoxic T-cells
        Induce apoptosis in target cells
      2. CD4+ helped T-cells
        Th1
        Activate macrophages to destroy pathogens
        B-cell activation roles
        Th2
        Interacts with B-cells mainly
        Th17
        Fight fungal infections
Innate Immune System
1. Response to an initial infection
  1. Immediate: 0-4 hours
    1. Infection
      1. Recognition by preformed, nonspecific and broadly specific effectors
        Removal of Infectious agent
2. Consists of Cells and Proteins
  1. Main components
    1. Physical epithelial barriers
    2. Phagocytic leukocytes
    3. Dendritic cells
    4. Special type ok lymphocyte - Natural Killer cell (NK)
    5. Circulating plasma proteins
Active Immune System
1. Injection a person with
  1. Antigens
2. Source of antibodies
  1. The person inoculated
3. Method
  1. Injection with
    1. Attenuated pathogens
    2. Their toxins
4. Time to develop resistance
  1. 5 to 14 days
5. Duration of resistance
  1. Long (Perhaps years)
6. When used
  1. Before Exposure to pathogen
Passive Immune System
1. Adquiere from the transfer of antibodies
  1. Produce by other person
2. protection decreases in a short time
  1. Weeks or months
3. Acquired Immunity
  1. Naturally
    1. Antibodies pass from mother to fetus
      1. Via placenta
      2. To infant in her milk
  2. Artificially
    1. Injection of immune serum
      1. Gamma globulin

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Classification of the Immune System

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	Created by Alma Cariño about 8 years ago