Notes
Arsenate poisoning
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Arsenate (AsO4 3-), being a salt of arsenic, is an analog of inorganic phosphate
since arsenic like phosphorus is in Group V of the periodic table.
Arsenate can produce an unstable analog of 1,3-bisphosphoglycerate called 1-
arseno-3-phosphoglycerate, by replacing a phosphate group.
1-arseno-3-phosphoglycerate can be rapidly hydrolyzed in water to produce 3-phosphoglycerate and inorganic arsenate is regenerated.
The ATP-producing reaction of glycolysis (step 7) involving 1,3-
bisphosphoglycerate is thereby bypassed, resulting in no net formation of ATP from glycolysis.
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- Scheduled for deletion Note on Arsenate poisoning, created by Jethro Broughton on 19/03/2016.
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- Jethro Broughton
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