Quiz
PHSI3011 08-1 Hormonal control of bone (PTH and sex steroids)
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Questions in this quiz (13)
1[blank_start]__________[blank_end] serum Calcium – sensed by Calcium-sensing Receptor (CaR) in the [blank_start]__________[blank_end] triggers release of PTH.
- ADecreased
- BIncreased
- CParaThyroid Gland
- DHypothalamus
- EThyroid Gland
2In response to decreased serum Calcium, PTH is released and goes to which of the following?
- AKidney
- BBone
- CGut
- DMuscle
- ELiver
3In the kidney, what PTH has 3 effects. These are:
a: [blank_start]_____[blank_end] 1,25 (OH)2 D;
b: [blank_start]_____[blank_end] Ca reabsorption;
c: [blank_start]_____[blank_end] PO4 reabsorption;- AIncrease
- BDecrease
- CIncrease
- DDecrease
- EIncrease
- FDecrease
4In the bone, PTH has 2 effects. These are:
a: ↑ [blank_start]__________[blank_end];
b: ↑ Bone [blank_start]__________[blank_end] (releasing Ca).- AOsteoclasts
- BOsteoblasts
- COsteocytes
- DLining Cells
- EResorption
- FFormation
5PTH-1 is a class-B GPCR. Yeah?
- AYeah
- BNah
6The primary effect of Hyperparathyroidism is:
- AIncrease blood Ca
- BDecrease blood Ca
- CIncrease kidney Ca
- DDecrease kidney Ca
7PROLONGED increase of PTH results in which of the following:
- AIncreased osteoclasts
- BDecreased osteoclasts
- CIncreased osteocytes
- DDecreased osteocytes
- EIncreased bone resorption
- FIncreased bone formation
- GBone loss
- HBone gain
8The main effect of INTERMITTENT PTH is:
- AIncreased osteoblast numbers
- BIncreased osteoclast numbers
- CDecreased osteoblast numbers
- DDecreased osteoclast numbers
9True or false: Intermittent PTH has little effect on osteoclasts, although they are necessary for its action.
- ATrue
- BFalse
10Sclerostin is a [blank_start]__________[blank_end] regulator of bone formation.
- ANegative
- BPositive
11Mutations that inactivate Sclerostin cause [blank_start]__________[blank_end] bone mass.
- AIncreased
- BDecreased
12Sclerostin is produced by which of the following:
- AOsteocytes
- BOsteoclasts
- COsteoblasts
- DLining Cells
- EPTH
13Intermittent PTH [blank_start]__________[blank_end] sclerostin. Sclerostin [blank_start]__________[blank_end] Wnt signaling. Therefore Intermittent PTH has a [blank_start]__________[blank_end] effect on Wnt signalling and results in [blank_start]__________[blank_end] bone formation (and [blank_start]__________[blank_end] bone resorption).
- ADecreases
- BIncreases
- CInhibits
- DStimulates
- EPositive
- FNegative
- GIncreased
- HDecreased
- IDecreased
- JIncreased
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- PHSI3011 08-1 Hormonal control of bone (PTH and sex steroids)
- Author
- Deleted user
- Language
- English
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- History
- Created on 10 Nov 2017 · updated on 10 Nov 2017
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