Quiz
L35: Growth Hormone
This quiz has question types that open in the usual player.
Questions in this quiz (18)
1What percent of cells in the anterior pituitary are somatotrophs, which produce growth hormone?
- A50%
- B20%
- C70%
- D95%
2Choose the incorrect statements.
- A20% of the cells in the anterior pituitary gland are mammotrophs.
- B20% of the cells in the anterior pituitary gland are corticotrophs.
- C50% of the cells in the anterior pituitary gland are thyrotrophs.
- D5% of the cells in the anterior pituitary gland are somatotrophs.
3SS stands for:
- ASomatostatin
- BSomastatin
- CSomatostatic
4Somatotrophin is another name for growth hormone.
- ATrue
- BFalse
5Growth hormone has been able to be produced in vitro since 1979.
- ATrue
- BFalse
6Growth hormone is a [blank_start]peptide[blank_end] hormone. It is [blank_start]small[blank_end] (191 amino acids). The secretion of GH is [blank_start]pulsatile[blank_end] and has a [blank_start]daily[blank_end] rhythm which differs between males and females.
- Apeptide
- Bprotein
- Csmall
- Dlong
- Epulsatile
- Fcontinuous
- Gdaily
- Hhourly
7Growth hormone's half life in the blood is 20-25 minutes.
- ATrue
- BFalse
8Growth hormone is an exception for [blank_start]peptide[blank_end] hormones because it travels in the [blank_start]blood bound to a protein carrier[blank_end].
- Apeptide
- Bprotein
- Cblood bound to a protein carrier
- Dwithout a protein carrier
9Growth hormone releasing hormone neurons (GHRH neurons) in the [blank_start]hypothalamus[blank_end] are excited and release [blank_start]GHRH[blank_end] into the anterior pituitary gland where it stimulates [blank_start]somatotrophs[blank_end] to release growth hormone (GH). GH is released into the bloodstream where it stimulates [blank_start]insulin-like growth factor (IGF-1)[blank_end] production in the [blank_start]liver[blank_end].
IGF-1 feeds back to the hypothalamus where it [blank_start]inhibits[blank_end] more release of GHRH and stimulates [blank_start]somatostatin (SS)[blank_end] to inhibit release of [blank_start]GH[blank_end] by the anterior pituitary gland.- Ahypothalamus
- BGHRH
- Csomatotrophs
- Dinsulin-like growth factor (IGF-1)
- Eliver
- Finhibits
- Gsomatostatin (SS)
- HGH
10Choose the correct statements.
- AGrowth hormone release peaks during the night and settles down during the day, but is constantly spiking.
- BThe growth hormone secretion peak is less pronounced for males.
- CRelease of GH increases with age until it peaks at puberty.
- DThe puberty peak of GH release occurs earlier for females than males.
11Growth hormone is essential for [blank_start]brain development[blank_end] until around age 8, rapid growth of [blank_start]height[blank_end] in two separate periods, and growth of [blank_start]reproductive organs[blank_end] around puberty.
- Abrain development
- Bheight
- Creproductive organs
12Growth hormone receptor is a single molecule found in the membrane that does not require activation.
- ATrue
- BFalse
13Which of these is not a long term effect of growth hormone?
- AStimulation of bone and muscle growth
- BStimulation of mitogenesis (cell division) via IGF-1
- CStimulation of protein synthesis (in liver)
14Stimulation of mitogenesis via IGF-1 is a direct effect of growth hormone.
Stimulation of protein synthesis in muscle by is an indirect effect of growth hormone.- ATrue
- BFalse
15Short term effects of growth hormone are always direct.
- ATrue
- BFalse
16Choose the correct effects of GH on metabolism(short term effects).
- AIncrease in blood glucose by stimulating glucose synthesis (in
liver) - BIncrease in blood glucose by stimulating cellular uptake of glucose
- CDecrease in triglyceride breakdown in adipose tissue
- DFree fatty acid mobilisation in adipose tissue
- AIncrease in blood glucose by stimulating glucose synthesis (in
17Other hormones important for [blank_start]growth[blank_end] are thyroid hormones, insulin, cortisol, and estrogen/testosterone.
Thyroid hormone [blank_start]increases[blank_end] the basal metabolic rate and is essential for [blank_start]nervous system[blank_end] development.
Insulin and [blank_start]cortisol[blank_end] increase [blank_start]glucose[blank_end] metabolism.
Estrogen/testosterone are essential during [blank_start]puberty[blank_end].- Agrowth
- Bincreases
- Cnervous system
- Dglucose
- Epuberty
- Fcortisol
18Endocrine disorders can be due to too little GH ([blank_start]hyposecretion[blank_end]) or too much GH ([blank_start]hypersecretion[blank_end]).
An [blank_start]excess[blank_end] of GH can cause gigantism or acromegaly. Acromegaly is an excess of GH in [blank_start]adulthood[blank_end] which leads to thickening of [blank_start]bones[blank_end], and of soft tissues in the hands, feet and face. A [blank_start]deficiency[blank_end] can cause dwarfism.
Endocrine disorders can also result from an issue in the GH [blank_start]receptors[blank_end]. Hyposensitive receptors [blank_start]give little or no response[blank_end] to GH and the effects are similar to hyposecretion. Hypersensitive receptors [blank_start]overreact[blank_end] to GH and have similar effects to hypersecretion.- Ahyposecretion
- Bhypersecretion
- Cexcess
- Dadulthood
- Echildhood
- Fbones
- Gmuscles
- Hdeficiency
- Ireceptors
- Jgive little or no response
- Koverreact
Information
- Description
- • Outline the sequence of events that results in the secretion of growth hormone. • Describe the metabolic effects of growth hormone on each type of target cell. • Describe the effects of growth hormone on human growth (during the growth years and after skeletal fusion) • Explain what occurs when there is too much or too little growth hormone secreted during childhood.
- Author
- Mer Scott
- Language
- English
- Views
- 116
- Tags
- Rating
- No ratings yet Rate this quiz