Quiz
Biochem lect 7 - free radicals and the human body
Questions in this quiz (16)
1Oxygen can be toxic
- ATrue
- BFalse
2Which of theses are reasons that oxygen is essential?
- AOxidation reactions
- BGeneration of ATP (oxidative phosphorylation)
- CDetoxification reactions
- DAnaerobic glycolysis
- EBio synthetic reactions
3Why is oxygen classified as toxic?
- AWhen it accepts single electrons it is transformed into highly reactive oxygen radicals than can damage things.
- BWhen it accepts double electrons it is transformed into highly reactive oxygen radicals than can damage things.
- CWhen it accepts single electrons it is transformed into non-reactive oxygen radicals than can damage things.
- DIt takes part in unnecessary reactions
4What do oxygen radicals damage?
- ACellular lipids
- BProteins
- CDNA
- DGlucose
- EStarch
5What are the major sources of primary ROS in the cell?
- ACoQ generates superoxide in ETC
- BRespiration in lungs
- COxidase, oxygenates and peroxidases
- DIonizing radiation
- ENon-ionizing radiation
6Where can evidence of free radical damage be seen?
- A>100 disease states
- B<100 disease states
- C>1000 disease states
7Where is evidence of free radical damage in disease states described?
- AAs primary cause of the disease
- BBy enhancing complications
- CIn the lumen of cells
8Superoxide and the hydroxyl radical Initiate lipid peroxidation in..
- ACellular membrane
- BMitochondrial membrane
- CNuclear membrane
- DER membrane
9Increase in membrane permeability due to radical-mediated damage leads to..
- AA further influx of ca2+
- BRepair of the mtiochondria
- CCa2+ leaving the cell
- DFurther escaping of radicals
10Oxidation of nuclear and mitochondrial DNA results in ...
- AStrand breaks
- BVarious damages
- CRNOS
- DInflux of Ca2+
11Disruption of the mitochondrial membrane may augment free radical damage
- ATrue
- BFalse
12Oxygen derived free radicals are a minor source of DNA damage
- ATrue
- BFalse
13The non-specific binding of Fe2+ to DNA...
- Afacilitates localized production of the hydroxyl radical
- BCan attack the deoxyribose backbone
- CCan cause strand breaks
- DWill cause apoptosis
- ECan be protective
14At high concentrations nitrogen combines with oxygen or superoxide to form reactive and toxic species which contain both N and O.
- ATrue
- BFalse
15RNOS’s are implicated in ...
- ANeurodegenerative diseases
- BChronic inflammatory diseases
- CHay fever
- DAlcoholism
- EHunger
16What are some of the consequences of high concentrations of NO during inflammation?
- AInhibition of enzymes
- BMitochondrial lipid peroxidation
- CInhibition of ETC and energy depletion
- DSingle or double strand breaks in DNA
- EModification of bases in DNA
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- biochem Quiz on Biochem lect 7 - free radicals and the human body, created by Alannah McDonnell on 05/03/2018.
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- Alannah McDonnell
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- English
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