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NSAIDs

gina_evans0312 21 questions 1,075 views

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Questions in this quiz (21)

  1. 1Why are some NSAIDs known as 'Traditional'?
    1. AThey only block one COX
    2. BThe block both COXs
  2. 2Describe COX1
    1. AConstituative
    2. BInducible
    3. CMembrane bound
    4. DCytoplasmic
  3. 3The channels of both COX1 & COX 2 are constricted to prevent incorrect substrate binding
    1. ATrue
    2. BFalse
  4. 4Where do NSAIDs bind on COX 1?
    1. AArg 120
    2. BArg 130
    3. CArg 140
  5. 5Aspirin binds permenantly to the Ser 530 of COX1
    1. ATrue
    2. BFalse
  6. 6Why does COX2 have a much wider channel than COX 1?
    1. AVal533 forces the channel to be wider
    2. BSer533 forces the channel to be wider
    3. CIle533 forces the channel to be wider
  7. 7COX2 is inducible
    1. ATrue
    2. BFalse
  8. 8The smaller channel of COX2 can be used for selective inhibition- i.e. Colecoxib
    1. ATrue
    2. BFalse
  9. 9COX2 is much less responsible for inflammation than COX1
    1. ATrue
    2. BFalse
  10. 10Why are selective COX2 inhibitors used on patients with G.I troubles?
    1. AThey also repair mucus membranes
    2. BThey have fewer side effects
    3. CThey cannot be digested properly by healthy tracts

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Description
Year 2 Quiz on NSAIDs, created by gina_evans0312 on 30/01/2014.
Language
English
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