Other RNAs

Other RNAs

1. RIBOSOMAL RNA

   • ROLE
     • Provides scaffolding for ribosomes
     • Has catalytic properties
     • Joins amino acids together during RNA translation
   • STRUCTURE OF RIBOSOME
     • Eukaryotes have 60s and 40s subunit which overall equals 80s
     • Prokaryotes have 50s and 30s which equals 70s overall

2. TRANSFER RNA

   • STRUCTURE
     • Anti codon amino acid attached to 3 prime
     • Longer end is 3 prime shorter end 5 prime
   • ROLE
     • Translates the message from the mRNA into a long polypeptide chain
   • WOBBLE
     • tRNAs use wobble to recognise the codon, in the third base of the anticodon. G can also pair with U
       • A modified base called I is also found this can base pair with A,C,U
         • Means that less tRNA needed
       • Normal base pairing still occurs
   • MANUFACTURE
     • Several tRNA transcribed together to form pre tRNA,
       • Pre tRNA folds up by base pairing
         • Cuts using RNAase P and D
           • Base Modification
           • Aminoacylation
             • AMP along with tRNA is attached to AARS with loss of pyrophosphate
             • AMP lost and tRNA charged

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