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Other Recruitment By Activated Tyrosine Kinase

gina_evans0312 Year 2 Inglés 15 fichas

Fichas del conjunto (15)

  1. 1p85Regulatory domain of Phosphatidynosityl-3-Kinase
  2. 2p110Catalytic domain of Phosphatidynosityl-3-Kinase
  3. 3Phosphatidynosityl-3-KinaseFamily of lipid kinases recruited to active tyrosine kinase
  4. 4Ras-GTPRequired for full PI-3-K activation
  5. 5Carbon of phosphatydinositol phosphorylated by PI-3-K3rd
  6. 6PTENReverses action of PI-3-Kinase
  7. 7Phosphorylated membrane lipidsPKB docking site
  8. 8No of PKB domains3
  9. 9PKB-Plecstrin Homology DomainBinds molecule to phosphorylated lipid & recruits signalling molecules to membrane
  10. 10Binding to membraneRequired for activation
  11. 11PDK1 & PDK2Phosphorylate & activate PKB
  12. 12mTORMassive lipid/protein kinase complex that binds to PKB
  13. 13Role of mTORPart of DNA damage repair family
  14. 14mTOR activates...Protein synthesis & cell growth
  15. 15PDK1 & 2 are .... activePermanently

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Year 2 Fichas sobre Other Recruitment By Activated Tyrosine Kinase, creado por gina_evans0312 el 02/12/2013.
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gina_evans0312
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