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Created by gina_evans0312
almost 12 years ago
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| Question | Answer |
| Polymorphism... | Allows recognition of non self proteins/cells |
| MCHI- Location | All nucleated cells |
| MCHI- Function | Display of viral proteins |
| MCHI- No of Types | 3 |
| MCHI- Alpha1 Chain | Anchors MCHI to membrane |
| MCHI- Beta2 | Non transmembrane- binds to Alpha1 covalently |
| MCHI- Alpha 3 and Beta 2 | Form an IgG like domain |
| MCHI- Size of Peptide Presented | 8-10 amino acids |
| MCHII- Location | Found solely in professional antigen presenting cells |
| MCHII- Alpha and Beta Chains | Both attach to cell membrane (no B2 domain) with an IgG like domain |
| Polygenism | Many genes availible |
| Polymorphic | Many alleles availbile |
| MHC is both polymorphic and polygenic | Accounting for its variation |
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